SCHEMBL1203776

SCHEMBL1203776

COc1cc(CCl)c(OCCC(C)CCCC(C)C)cc1CCl

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 5/20 0.38
LMNA P02545 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
FDPS P14324 1/20 0.33
ALOX5 P09917 1/20 0.33
TRPV1 Q8NER1 1/20 0.33
TLR8 Q9NR97 1/20 0.33
C5 P01031 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6858909 0.94 LMNA (0.41) HTR2ALMNAFDPSALOX5TLR8
SCHEMBL5712240 0.87 HTR2A (0.39) HTR2ALMNATAAR1FDPSALOX5
SCHEMBL3900419 0.86 HTR2A (0.32) HTR2ATAAR1
SCHEMBL6075237 0.86 HTR2A (0.32) HTR2ATAAR1
SCHEMBL1204813 0.86 PDE4A (0.40) HTR2ALMNATAAR1FDPSALOX5
SCHEMBL19474674 0.84 HTR2A (0.35) HTR2A
SCHEMBL6075405 0.84 HTR2A (0.31) HTR2A
SCHEMBL6075682 0.84 HTR2A (0.31) HTR2A
SCHEMBL7030818 0.84 MTNR1B (0.40) HTR2ALMNATAAR1FDPSALOX5
SCHEMBL4329423 0.83 MGAM (0.43) FDPSALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6824892-B2 MAIN CHAIN OF PHENYLENE VINYLENE AND A SIDE CHAIN OF CARBAZOLE AND AN ALIPHATIC ALKYL OR ALKOXY GROUP SAMSUNG SDI CO., LTD. (KR) 2004-11-30 US claimed
US-20020093005-A1 Electroluminescent polymer having good carrier transport balance and electroluminescent device using the same SAMSUNG SDI CO., LTD. 2002-07-18 US claimed
US-7884175-B2 polymerizing one or more monomers containing dihalogen containing substituted biaryls, via a base-induced dehydrohalogenation MERCK PATENT GMBH (DE) 2011-02-08 US disclosed
US-7446164-B2 Method of preparing derivatives of polyarylene vinylene and method of preparing an electronic device including same INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM (IMEC) (BE) 2008-11-04 US disclosed
US-20070287816-A1 METHOD OF PREPARING DERIVATIVES OF POLYARYLENE VINYLENE AND METHOD OF PREPARING AN ELECTRONIC DEVICE INCLUDING SAME INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM (IMEC) (BE) 2007-12-13 US disclosed
EP-1623471-B1 METHOD FOR CONTROLLING THE MOLECULAR WEIGHT DURING POLY(ARYLENE VINYLENE) SYNTHESIS, AND POLYMERS PRODUCED THEREWITH MERCK PATENT GMBH (DE) 2007-05-30 EP disclosed
EP-1161478-B1 TRIPTYCENE POLYMERS AND COPOLYMERS COVION ORGANIC SEMICONDUCTORS (DE) 2006-12-27 EP disclosed
US-20060247415-A1 Method for controlling the molecular weight during poly(arylene vinylene) synthesis, and polymers produced therewith MERCK PATENT GMBH (DE) 2006-11-02 US disclosed
US-7087787-B1 Method for producing derivatives of 4-alkylsulfinyl methylarylene methanols COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2006-08-08 US disclosed
US-7041388-B1 Substituted poly(arylene vinylenes), process for their preparation and their use in electroluminescent devices SEMICONDUCTORS GMBH (DE) 2006-05-09 US disclosed
EP-1623471-A1 METHOD FOR CONTROLLING THE MOLECULAR WEIGHT DURING POLY(ARYLENE VINYLENE) SYNTHESIS, AND POLYMERS PRODUCED THEREWITH Covion Organic Semiconductors GmbH (DE) 2006-02-08 EP disclosed
EP-1161478-A1 TRIPTYCENE POLYMERS AND COPOLYMERS Celanese Ventures GmbH (DE) 2001-12-12 EP disclosed
EP-0963686-B1 ORGANIC ELECTROLUMINESCENT DEVICE KONINKL PHILIPS ELECTRONICS NV (NL) 2001-12-12 EP disclosed
WO-2001034722-A1 SUBSTITUTED POLY(ARYLENE VINYLENES), METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN ELECTROLUMINESCENT DEVICES COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2001-05-17 WO disclosed
WO-2000053655-A1 TRIPTYCENE POLYMERS AND COPOLYMERS CELANESE VENTURES GMBH (DE) 2000-09-14 WO disclosed
EP-1029019-A1 SUBSTITUTED POLY(ARYLENE VINYLENES), METHOD FOR PRODUCING THE SAME, AND THEIR USE IN ELECTROLUMINESCENT ELEMENTS Axiva GmbH (DE) 2000-08-23 EP disclosed
US-6054725-A Organic electroluminescent device U.S. PHILIPS CORPORATION (US) 2000-04-25 US disclosed
EP-0944663-A1 ARYL-SUBSTITUTED POLY(p-ARYLENE VINYLENES), METHOD FOR THE PRODUCTION AND USE THEREOF IN ELECTROLUMINESCENT COMPONENTS Celanese Ventures GmbH (DE) 1999-09-29 EP disclosed
WO-1999024526-A1 SUBSTITUTED POLY(ARYLENE VINYLENES), METHOD FOR PRODUCING THE SAME, AND THEIR USE IN ELECTROLUMINESCENT ELEMENTS AXIVA GMBH (DE) 1999-05-20 WO disclosed
WO-1998027136-A1 ARYL-SUBSTITUTED POLY(p-ARYLENE VINYLENES), METHOD FOR THE PRODUCTION AND USE THEREOF IN ELECTROLUMINESCENT COMPONENTS AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) 1998-06-25 WO disclosed