SCHEMBL6858909

SCHEMBL6858909

CC(C)CCCC(C)CCOc1cc(CCl)c(OCCC(C)CCCC(C)C)cc1CCl

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
FDPS P14324 2/20 0.36
ALOX5 P09917 1/20 0.36
TLR8 Q9NR97 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
GGPS1 O95749 1/20 0.33
EGFR P00533 2/20 0.33
GSTO1 P78417 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
BLM P54132 1/20 0.33
HTT P42858 1/20 0.32
LTB4R Q15722 1/20 0.32
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
THRA P10827 1/20 0.31
THRB P10828 1/20 0.31
MCHR1 Q99705 1/20 0.30
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1203776 0.94 HTR2A (0.38) LMNAFDPSALOX5TLR8HTR2A
SCHEMBL6860303 0.86 TDP1 (0.36) FDPSALOX5TLR8TDP1GGPS1
SCHEMBL7030818 0.83 MTNR1B (0.40) LMNAFDPSALOX5TDP1MAPT
SCHEMBL3900419 0.81 HTR2A (0.32) HTR2A
SCHEMBL6075237 0.81 HTR2A (0.32) HTR2A
SCHEMBL5712240 0.80 HTR2A (0.39) LMNAFDPSALOX5TLR8HTR2A
SCHEMBL6075405 0.80 HTR2A (0.31) HTR2A
SCHEMBL19474674 0.80 HTR2A (0.35) HTR2A
SCHEMBL6075682 0.80 HTR2A (0.31) HTR2A
SCHEMBL6249872 0.79 LMNA (0.36) LMNAFDPSALOX5TLR8GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1029019-B1 SUBSTITUTED POLY(ARYLENE VINYLENES), METHOD FOR PRODUCING THE SAME, AND THEIR USE IN ELECTROLUMINESCENT ELEMENTS COVION ORGANIC SEMICONDUCTORS (DE) 2004-03-03 EP disclosed
US-6638646-B2 Polymerizing one or more monomers containing dihalogen containing substituted biaryls, via a base-induced dehydrohalogenation SEMICONDUCTORS GMBH (DE) 2003-10-28 US disclosed
US-20030088050-A1 Substituted poly(arylenevinylenes), process for their preparation, and their use in electroluminescent elements MERCK PATENT GMBH (DE) 2003-05-08 US disclosed
US-6458909-B1 SOLID-STATE LIGHT SOURCES FOR A SERIES OF APPLICATIONS, PREDOMINANTLY IN THE FIELD OF DISPLAY ELEMENTS HOECHST AKTIENGESELLSCHAFT (DE) 2002-10-01 US disclosed
US-20020064680-A1 Substituted poly(arylene vinylenes), method for producing the same, and their use in electroluminescent elements AXIVA GMBH (DE) 2002-05-30 US disclosed
EP-0944663-B1 ARYL-SUBSTITUTED POLY(p-ARYLENE VINYLENES), METHOD FOR THE PRODUCTION AND USE THEREOF IN ELECTROLUMINESCENT COMPONENTS CELANESE VENTURES GMBH (DE) 2002-03-27 EP disclosed
EP-1029019-A1 SUBSTITUTED POLY(ARYLENE VINYLENES), METHOD FOR PRODUCING THE SAME, AND THEIR USE IN ELECTROLUMINESCENT ELEMENTS Axiva GmbH (DE) 2000-08-23 EP disclosed
EP-0944663-A1 ARYL-SUBSTITUTED POLY(p-ARYLENE VINYLENES), METHOD FOR THE PRODUCTION AND USE THEREOF IN ELECTROLUMINESCENT COMPONENTS Celanese Ventures GmbH (DE) 1999-09-29 EP disclosed
WO-1999024526-A1 SUBSTITUTED POLY(ARYLENE VINYLENES), METHOD FOR PRODUCING THE SAME, AND THEIR USE IN ELECTROLUMINESCENT ELEMENTS AXIVA GMBH (DE) 1999-05-20 WO disclosed
WO-1998027136-A1 ARYL-SUBSTITUTED POLY(p-ARYLENE VINYLENES), METHOD FOR THE PRODUCTION AND USE THEREOF IN ELECTROLUMINESCENT COMPONENTS AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) 1998-06-25 WO disclosed