SCHEMBL12039540

SCHEMBL12039540

Cc1ccc2c(-c3ccc(C(=O)C(C)(C)C)cc3C(=O)O)c3ccc(=O)cc-3oc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.55
▸ L3MBTL1 Q9Y468 1/20 0.55
▸ CA9 Q16790 11/20 0.47
▸ POLB P06746 3/20 0.46
▸ MEN1 O00255 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ ALPL P05186 1/20 0.46
▸ ALPI P09923 1/20 0.46
▸ ALPG P10696 1/20 0.46
▸ CA1 P00915 9/20 0.44
▸ CA2 P00918 9/20 0.44
▸ ATM Q13315 1/20 0.43
▸ PLEC Q15149 1/20 0.43
▸ ESR1 P03372 1/20 0.43
▸ CA12 O43570 3/20 0.42
▸ DNASE1L3 Q13609 1/20 0.42
▸ PRMT1 Q99873 1/20 0.42
▸ KDM4E B2RXH2 1/20 0.40
▸ CA14 Q9ULX7 2/20 0.40
▸ ALB P02768 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19449068 0.90 USP2 (0.69) USP2L3MBTL1CA9POLBMEN1
SCHEMBL13401323 0.83 USP2 (0.62) USP2L3MBTL1CA9POLBMEN1
SCHEMBL10060277 0.83 POLB (0.59) USP2L3MBTL1CA9POLBMEN1
SCHEMBL20990646 0.82 USP2 (0.67) USP2L3MBTL1CA9POLBMEN1
SCHEMBL10098714 0.82 USP2 (0.76) USP2L3MBTL1CA9POLBMEN1
SCHEMBL10177784 0.82 USP2 (0.38) USP2L3MBTL1CA9POLBMEN1
SCHEMBL12637546 0.81 USP2 (0.57) USP2L3MBTL1CA9POLBMEN1
SCHEMBL14302317 0.80 USP2 (0.48) USP2L3MBTL1CA9POLBMEN1
SCHEMBL10014172 0.80 CA9 (0.56) USP2L3MBTL1CA9POLBMEN1
SCHEMBL7006557 0.79 ABCB1 (0.50) USP2L3MBTL1CA9POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110319339-A1 NEUROTENSIN-DERIVED BRANCHED PEPTIDES AND USES THEREOF BRACCI LUISA (IT) 2011-12-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110319339-A1 NEUROTENSIN-DERIVED BRANCHED PEPTIDES AND USES THEREOF NTSR1, NTSR2, NGLY1 USP2 4238/4885L3MBTL1 1348/4885CA9 554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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