SCHEMBL13401323

SCHEMBL13401323

CC(C)(C)C(=O)c1ccc(C(=O)O)c(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c1

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.62
▸ L3MBTL1 Q9Y468 1/20 0.62
▸ DNASE1L3 Q13609 1/20 0.58
▸ PRMT1 Q99873 1/20 0.58
▸ MEN1 O00255 2/20 0.57
▸ POLB P06746 2/20 0.57
▸ KMT2A Q03164 2/20 0.57
▸ ALPL P05186 1/20 0.57
▸ ALPI P09923 1/20 0.57
▸ ALPG P10696 1/20 0.57
▸ ATM Q13315 1/20 0.55
▸ PLEC Q15149 1/20 0.55
▸ CA9 Q16790 10/20 0.50
▸ CA1 P00915 8/20 0.49
▸ CA2 P00918 8/20 0.49
▸ ALB P02768 1/20 0.49
▸ ESR1 P03372 1/20 0.48
▸ CA12 O43570 2/20 0.47
▸ CA14 Q9ULX7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19449068 0.93 USP2 (0.69) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL23318854 0.90 USP2 (0.57) USP2L3MBTL1DNASE1L3PRMT1MEN1
6-Carboxyfluorescein SCHEMBL29369299 0.90 USP2 (0.69) USP2L3MBTL1DNASE1L3PRMT1MEN1
6-Carboxyfluorescein SCHEMBL9906208 0.90 USP2 (0.69) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL12061907 0.89 USP2 (0.66) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL12604830 0.87 USP2 (0.69) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL14642481 0.86 USP2 (0.62) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL13785142 0.86 DNASE1L3 (0.63) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL13880697 0.86 USP2 (0.62) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL19370241 0.86 USP2 (0.64) USP2L3MBTL1DNASE1L3PRMT1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240207423-A1 PROGAMMABLE POLYMERIC DRUGS SONY GROUP CORP (JP) 2024-06-27 — — US disclosed
US-11874280-B2 Use of divalent metals for enhancement of fluorescent signals Sony Group Corporation (JP) 2024-01-16 — — US disclosed
US-11874280-B2 Use of divalent metals for enhancement of fluorescent signals Sony Group Corporation (JP) 2024-01-16 — — US disclosed
WO-2023242661-A2 POLYMERIC TANDEM DYES WITH SPACING LINKER GROUPS Sony Group Corporation (JP) 2023-12-21 — — WO disclosed
US-20230129481-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS Sony Group Corporation (JP) 2023-04-27 — — US disclosed
US-20230129481-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS Sony Group Corporation (JP) 2023-04-27 — — US disclosed
US-20230012304-A1 POLYMERIC TANDEM DYES WITH LINKER GROUPS Sony Group Corporation (JP) 2023-01-12 — — US disclosed
US-20220402963-A1 NUCLEOTIDE PROBES Sony Group Corporation (JP) 2022-12-22 — — US disclosed
US-11352502-B2 Polymeric tandem dyes with linker groups Sony Group Corporation (JP) 2022-06-07 — — US disclosed
US-20220168433-A1 PROGRAMMABLE POLYMERIC DRUGS Sony Group Corporation (JP) 2022-06-02 — — US disclosed
US-10041115-B2 3′-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing LASERGEN, INC. (US) 2018-08-07 — — US disclosed
US-20180164322-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS SONY CORPORATION (JP) 2018-06-14 — — US disclosed
US-9851359-B2 Ultra bright dimeric or polymeric dyes with spacing linker groups SONY CORPORATION OF AMERICA (US) 2017-12-26 — — US disclosed
US-9851359-B2 Ultra bright dimeric or polymeric dyes with spacing linker groups SONY CORPORATION OF AMERICA (US) 2017-12-26 — — US disclosed
US-20170327886-A1 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING LASERGEN, INC. (US) 2017-11-16 — — US disclosed
US-20170292957-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS SONY CORPORATION (JP) 2017-10-12 — — US disclosed
US-20170292957-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS SONY CORPORATION (JP) 2017-10-12 — — US disclosed
US-9689035-B2 3′-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing LASERGEN, INC. (US) 2017-06-27 — — US disclosed
US-8354523-B2 Oligonucleotide probes and uses thereof ALLELOGIC BIOSCIENCES CORPORATION (US) 2013-01-15 — — US disclosed
US-20100086916-A1 OLIGONUCLEOTIDE PROBES AND USES THEREOF ALLELOGIC BIOSCIENCES CORPORATION 2010-04-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220402963-A1 NUCLEOTIDE PROBES METTL3, SNRPA, L3MBTL3 USP2 3222/4885L3MBTL1 10/4885DNASE1L3 847/4885
US-11352502-B2 Polymeric tandem dyes with linker groups CHRM1, IK, TMT1A USP2 2688/4885L3MBTL1 20/4885DNASE1L3 2399/4885
US-20220168433-A1 PROGRAMMABLE POLYMERIC DRUGS CHRM1, PBRM1, CHRM2 USP2 1989/4885L3MBTL1 15/4885DNASE1L3 830/4885
US-20180164322-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS IK, MTCL3, RRM1 USP2 699/4885L3MBTL1 27/4885DNASE1L3 1738/4885
US-10041115-B2 3′-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing RNGTT, NT5C3B, NSUN2 USP2 1610/4885L3MBTL1 205/4885DNASE1L3 176/4885
US-20100086916-A1 OLIGONUCLEOTIDE PROBES AND USES THEREOF POLRMT, DCLRE1B, RNGTT USP2 2982/4885L3MBTL1 731/4885DNASE1L3 118/4885
US-20240207423-A1 PROGAMMABLE POLYMERIC DRUGS OPRM1, CHRM1, TUBB3 USP2 3217/4885L3MBTL1 444/4885DNASE1L3 2447/4885
US-20170327886-A1 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING RNGTT, NT5C3B, NSUN2 USP2 1587/4885L3MBTL1 196/4885DNASE1L3 170/4885
US-20230129481-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS IK, MTCL3, RRM1 USP2 699/4885L3MBTL1 27/4885DNASE1L3 1738/4885
US-20230012304-A1 POLYMERIC TANDEM DYES WITH LINKER GROUPS CHRM1, MTCL3, TMT1A USP2 2719/4885L3MBTL1 22/4885DNASE1L3 2554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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