Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19669784 | 0.85 | ALDH1A1 (0.34) | NPSR1GLO1ALDH1A1TSHRLMNA | |
| SCHEMBL2204826 | 0.80 | ALDH1A1 (0.43) | NPSR1GLO1ALDH1A1TSHRLMNA | |
| SCHEMBL17225470 | 0.80 | BIRC2 (0.31) | ALDH1A1 | |
| SCHEMBL2253759 | 0.80 | ALDH1A1 (0.33) | NPSR1GLO1ALDH1A1TSHRLMNA | |
| SCHEMBL6676758 | 0.78 | ALDH1A1 (0.42) | NPSR1GLO1ALDH1A1TSHRLMNA | |
| SCHEMBL1088298 | 0.78 | ALDH1A1 (0.42) | NPSR1GLO1ALDH1A1TSHRLMNA | |
| SCHEMBL6674982 | 0.78 | ALDH1A1 (0.42) | NPSR1GLO1ALDH1A1TSHRLMNA | |
| SCHEMBL23462063 | 0.78 | MMP8 (0.31) | NPSR1GLO1 | |
| SCHEMBL29918740 | 0.78 | MMP8 (0.31) | NPSR1GLO1 | |
| SCHEMBL2262673 | 0.76 | CA1 (0.38) | NPSR1GLO1ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292779-B1 | Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses thereof | UNIV PENNSYLVANIA (US) | 2016-11-16 | — | — | EP | disclosed |
| US-20150353991-A1 | MIRNA TARGETS | CHILDREN'S MEDICAL CENTER CORPORATION | 2015-12-10 | — | — | US | disclosed |
| WO-2014179765-A2 | NOVEL HUMAN MIRNAS FOR USE IN DIAGNOSIS, PROGNOSIS AND THERAPY OF HUMAN CONDITIONS AND DISEASES | THOMAS JEFFERSON UNIVERSITY (US) | 2014-11-06 | — | — | WO | disclosed |
| US-20110300205-A1 | SELF REPLICATING RNA MOLECULES AND USES THEREOF | NOVARTIS AG (CH) | 2011-12-08 | — | — | US | disclosed |
| US-7649019-B2 | controlled release tablet of bupropion hydrobromide for reducing the ratio of the maximum/minimum plasma bupropion hydrobromide concentration (Cmax/Cmin) while maintaining bupropion plasma levels within the therapeutic window upon administration to a patient; more stable than buproin hcl | BIOVAIL LABORATORIES INTERNATIONAL S.R.L. (BB) | 2010-01-19 | — | — | US | disclosed |