Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23462063 | 1.00 | MMP8 (0.31) | MMP8PKMNPSR1GLO1 | |
| SCHEMBL23461547 | 0.85 | — | — | |
| SCHEMBL23461546 | 0.85 | — | — | |
| SCHEMBL23461670 | 0.85 | — | — | |
| SCHEMBL30099966 | 0.85 | — | — | |
| SCHEMBL26326766 | 0.85 | — | — | |
| SCHEMBL19669784 | 0.81 | ALDH1A1 (0.34) | NPSR1GLO1 | |
| SCHEMBL12041111 | 0.78 | NPSR1 (0.32) | NPSR1GLO1 | |
| SCHEMBL2204826 | 0.76 | ALDH1A1 (0.43) | NPSR1GLO1 | |
| SCHEMBL2253759 | 0.76 | ALDH1A1 (0.33) | NPSR1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4069691-A1 | SUBSTITUTED TETRAHYDROFURANS AS MODULATORS OF SODIUM CHANNELS | Vertex Pharmaceuticals Incorporated (US) | 2022-10-12 | — | — | EP | disclosed |