SCHEMBL120453

SCHEMBL120453

O=C(O)c1ccccc1C(=O)OCC(O)CO

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
TSHR P16473 2/20 0.54
ADRB2 P07550 9/20 0.47
ADRB1 P08588 9/20 0.47
ADRB3 P13945 9/20 0.47
ALOX15 P16050 1/20 0.47
CYP3A4 P08684 3/20 0.45
MAPK1 P28482 2/20 0.45
HSD17B10 Q99714 2/20 0.45
KDM4E B2RXH2 1/20 0.45
MLNR O43193 1/20 0.45
ABCB11 O95342 1/20 0.45
CHRM2 P08172 1/20 0.45
ADORA3 P0DMS8 1/20 0.45
CHRM1 P11229 1/20 0.45
GABRA1 P14867 1/20 0.45
HPGD P15428 1/20 0.45
TBXA2R P21731 1/20 0.45
PTGS1 P23219 1/20 0.45
SLC6A2 P23975 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL120454 0.93 ALDH1A1 (0.61) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL9417359 0.91 ALDH1A1 (0.61) ALDH1A1TSHRADRB2ADRB1ADRB3
Glycerin SCHEMBL28305862 0.87 ALDH1A1 (0.50) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL9106286 0.87 ALDH1A1 (0.54) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL28203417 0.86 ALDH1A1 (0.42) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL1513876 0.85 ALDH1A1 (0.57) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL828389 0.84 ALDH1A1 (0.61) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL9106298 0.84 ALDH1A1 (0.45) ALDH1A1TSHRALOX15CYP3A4KDM4E
SCHEMBL17629572 0.83 ADRB2 (0.63) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL17629569 0.83 ADRB2 (0.63) ALDH1A1TSHRADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 602 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240327694-A1 HEAT-TRANSFER LIQUID SOLUTION, AND RELATED METHODS OF MAKING AND USING SEAGATE TECHNOLOGY LLC 2024-10-03 US claimed
US-11795636-B2 Systems and methods for making thermoplastic products and compositions ENNIS-FLINT, INC. (US) 2023-10-24 US claimed
EP-3307823-B1 DURABLE DEBRIS AND ALKALINE RESISTANT PREFORMED THERMOPLASTIC RUNWAY PAVEMENT MARKING COMPOSITIONS ENNIS FLINT INC (US) 2023-08-16 EP claimed
CN-113573862-B System and method for manufacturing thermoplastic products and compositions 恩尼斯-弗林特股份有限公司 2023-05-26 CN claimed
US-11613655-B2 Systems and methods for making thermoplastic products and compositions ENNIS-FLINT, INC. (US) 2023-03-28 US claimed
US-11279259-B2 Load supporting and insulating apparatuses for rails PRECISION RAIL AND MFG., INC. (US) 2022-03-22 US claimed
EP-3962709-A1 SYSTEMS AND METHODS FOR MAKING THERMOPLASTIC PRODUCTS AND COMPOSITIONS Ennis-Flint, Inc. (US) 2022-03-09 EP claimed
CN-114007838-A Systems and methods for manufacturing thermoplastic products and compositions 恩尼斯-弗林特股份有限公司 2022-02-01 CN claimed
EP-3911486-A1 SYSTEMS AND METHODS FOR MAKING THERMOPLASTIC PRODUCTS AND COMPOSITIONS Ennis-Flint, Inc. (US) 2021-11-24 EP claimed
CN-113573862-A Systems and methods for manufacturing thermoplastic products and compositions 恩尼斯-弗林特股份有限公司 2021-10-29 CN claimed
EP-1181983-A2 Spray gun for enteric coating and process for producing enteric coated preparation SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-02-27 EP claimed
US-5929204-A Process for removing metals from vinylphenol-type polymers MARUZEN PETROCHEMICAL CO., LTD. (JP) 1999-07-27 US claimed
EP-0860451-A1 Process for removing metals from vinylphenol-type polymers MARUZEN PETROCHEMICAL CO., LTD. (JP) 1998-08-26 EP claimed
US-5470924-A Phenol formaldehyde resins RYAN BARRY W (AU) 1995-11-28 US claimed
CN-1085572-A Improved phenolic resins RYAN BARRY WILLIAM (AU) 1994-04-20 CN claimed
WO-1992017528-A1 IMPROVED PHENOL FORMALDEHYDE RESINS RYAN BARRY WILLIAM (AU) 1992-10-15 WO claimed
US-4921695-A Antianginal plate for treating ischemic heart disease VSESOJUZNY NAUCHNO-ISSLEDOVATELSKY TSENTR PROFILAKTICHESKOI MEDITSINY - USSR 1990-05-01 US claimed
US-4756991-A Pigmented resin particles coated with silicone oil and water soluble polymeric quaternary ammonium compound; nonelectroscopic E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-07-12 US claimed
US-4713239-A ABSORPTION THROUGH THE MUCOUS MEMBRANES OF THE MOUTH VSESOJUNY KARDIOLOGICHESKY NAUCHNY TSENTR ADKAEMII MEDITSINSKI NAUK SSSR (SU) 1987-12-15 US claimed
US-RE31309-E HYDROXYALKYL ACRYLATE MONOMER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-07-12 US claimed