SCHEMBL9106286

SCHEMBL9106286

O=C(OO)c1ccccc1C(=O)OCC(O)CO

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
TSHR P16473 2/20 0.54
ADRB2 P07550 11/20 0.49
ADRB1 P08588 11/20 0.49
ADRB3 P13945 11/20 0.49
NPC1 O15118 1/20 0.46
CYP3A4 P08684 3/20 0.45
MAPK1 P28482 2/20 0.45
HSD17B10 Q99714 2/20 0.45
KDM4E B2RXH2 1/20 0.45
MLNR O43193 1/20 0.45
ABCB11 O95342 1/20 0.45
CHRM2 P08172 1/20 0.45
ADORA3 P0DMS8 1/20 0.45
CHRM1 P11229 1/20 0.45
GABRA1 P14867 1/20 0.45
HPGD P15428 1/20 0.45
TBXA2R P21731 1/20 0.45
PTGS1 P23219 1/20 0.45
SLC6A2 P23975 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL120454 0.93 ALDH1A1 (0.61) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL120453 0.87 ALDH1A1 (0.56) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL446204 0.83 ADRB2 (0.63) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL29613210 0.83 ADRB2 (0.63) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL17629569 0.83 ADRB2 (0.63) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL17629572 0.83 ADRB2 (0.63) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL28305861 0.83 ALDH1A1 (0.55) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL30002317 0.82 ADRB2 (0.68) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL15736 0.82 ALDH1A1 (0.58) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL29875753 0.82 ALDH1A1 (0.58) ALDH1A1TSHRADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5451654-A Addition polymerization catalyst ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-09-19 US disclosed
US-5387654-A Hydroxy-peroxides and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-02-07 US disclosed
EP-0381135-B1 Novel hydroxy-peroxides and their uses ATOCHEM NORTH AMERICA (US) 1994-06-01 EP disclosed
US-5304649-A Curing agent for unsaturated polyesters ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-04-19 US disclosed
EP-0381135-A2 Novel hydroxy-peroxides and their uses ATOCHEM NORTH AMERICA, INC. (US) 1990-08-08 EP disclosed