Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 2/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | BCR | P11274 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 3/20 | 0.36 |
| ▸ | CDK4 | P11802 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | ROS1 | P08922 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12046555 | 0.93 | PRKCA (0.41) | TDO2PRKCABRAFKDRABL1 | |
| SCHEMBL12046560 | 0.92 | IGF1R (0.41) | TDO2BRAFKDRABL1BCR | |
| SCHEMBL12046502 | 0.89 | MAPT (0.36) | TDO2PRKCABRAFKDRNPC1 | |
| SCHEMBL12046354 | 0.88 | CA12 (0.34) | TDO2BRAFKDRNPC1RAB9A | |
| SCHEMBL8909785 | 0.87 | SCN9A (0.37) | TDO2PRKCAKDRABL1BCR | |
| SCHEMBL12046552 | 0.85 | MEN1 (0.36) | PRKCANPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL12046333 | 0.83 | MAPT (0.36) | PRKCASMN1; SMN2EGFRMETROS1 | |
| SCHEMBL12046451 | 0.81 | EGFR (0.37) | PRKCANPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL1323147 | 0.80 | KMT2A (0.39) | NPC1RAB9ASMN1; SMN2EGFRMET | |
| SCHEMBL1323149 | 0.80 | KMT2A (0.39) | NPC1RAB9ASMN1; SMN2EGFRMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110319615-A1 | INSECTICIDAL PYRIMIDINYL ARYL HYRDRAZONES | DOW AGROSCIENCES LLC (US) | 2011-12-29 | — | — | US | disclosed |
| US-20110319615-A1 | INSECTICIDAL PYRIMIDINYL ARYL HYRDRAZONES | DOW AGROSCIENCES LLC (US) | 2011-12-29 | — | — | US | disclosed |
| US-8058279-B2 | Insecticidal pyrimidinyl aryl hyrdrazones | DOW AGROSCIENCES LLC (US) | 2011-11-15 | — | — | US | disclosed |
| US-8058279-B2 | Insecticidal pyrimidinyl aryl hyrdrazones | DOW AGROSCIENCES LLC (US) | 2011-11-15 | — | — | US | disclosed |
| US-20090093480-A1 | INSECTICIDAL PYRIMIDINYL ARYL HYRDRAZONES | DOW AGROSCIENCES LLC (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090093480-A1 | INSECTICIDAL PYRIMIDINYL ARYL HYRDRAZONES | DOW AGROSCIENCES LLC (US) | 2009-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093480-A1 | INSECTICIDAL PYRIMIDINYL ARYL HYRDRAZONES | DDT, HELZ, HPD | TDO2 1841/4885PRKCA 4346/4885BRAF 3056/4885 |
| US-20110319615-A1 | INSECTICIDAL PYRIMIDINYL ARYL HYRDRAZONES | DDT, HELZ, HPD | TDO2 1841/4885PRKCA 4346/4885BRAF 3056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.