SCHEMBL1204753

SCHEMBL1204753

CCCCCCCCC(CCC)[Si](Cl)(Cl)Cl

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
DNM1 Q05193 2/20 0.39
TSHR P16473 2/20 0.38
THRB P10828 1/20 0.38
OPRM1 P35372 1/20 0.37
ALDH1A1 P00352 1/20 0.36
GPR84 Q9NQS5 3/20 0.35
FDPS P14324 3/20 0.35
SPHK1 Q9NYA1 1/20 0.35
FFAR1 O14842 1/20 0.35
MAPT P10636 1/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29093845 1.00 LMNA (0.39) LMNADNM1TSHRTHRBOPRM1
SCHEMBL2297383 1.00 LMNA (0.39) LMNADNM1TSHRTHRBOPRM1
SCHEMBL30803745 0.95 LMNA (0.42) LMNADNM1TSHRTHRBOPRM1
SCHEMBL3725398 0.95 LMNA (0.42) LMNADNM1TSHRTHRBOPRM1
SCHEMBL28418766 0.95 LMNA (0.42) LMNADNM1TSHRTHRBOPRM1
SCHEMBL28675045 0.95 LMNA (0.42) LMNADNM1TSHRTHRBOPRM1
SCHEMBL1903588 0.95 LMNA (0.42) LMNADNM1TSHRTHRBOPRM1
SCHEMBL7895556 0.95 LMNA (0.42) LMNADNM1TSHRTHRBOPRM1
SCHEMBL27811476 0.90 LMNA (0.33) LMNADNM1TSHRTHRBOPRM1
SCHEMBL7904554 0.86 DNM1 (0.42) LMNADNM1TSHRTHRBOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404876-B2 Process for producing nanoparticles 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-03-26 US disclosed
EP-2297172-B1 PROCESS FOR PRODUCING NANOPARTICLES 3M INNOVATIVE PROPERTIES CO (US) 2012-06-27 EP disclosed
CN-102076784-A Surface-modified nanoparticles 3M INNOVATIVE PROPERTIES CO 2011-05-25 CN disclosed
EP-2297172-A2 PROCESS FOR PRODUCING NANOPARTICLES 3M Innovative Properties Company (US) 2011-03-23 EP disclosed
EP-2291460-A2 SURFACE-MODIFIED NANOPARTICLES 3M Innovative Properties Company (US) 2011-03-09 EP disclosed
US-20110046404-A1 PROCESS FOR PRODUCING NANOPARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2011-02-24 US disclosed
US-20110039947-A1 SURFACE-MODIFIED NANOPARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2011-02-17 US disclosed
WO-2009137592-A2 SURFACE-MODIFIED NANOPARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-11-12 WO disclosed
WO-2009137595-A2 PROCESS FOR PRODUCING NANOPARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-11-12 WO disclosed