SCHEMBL1903588

SCHEMBL1903588

CCCCCCCCCCC(CCCCC)[Si](Cl)(Cl)Cl

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
TSHR P16473 2/20 0.42
THRB P10828 1/20 0.42
DNM1 Q05193 2/20 0.42
OPRM1 P35372 1/20 0.40
ALDH1A1 P00352 1/20 0.39
GPR84 Q9NQS5 3/20 0.38
FDPS P14324 3/20 0.38
SPHK1 Q9NYA1 1/20 0.38
FFAR1 O14842 1/20 0.38
MAPT P10636 1/20 0.37
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28418766 1.00 LMNA (0.42) LMNATSHRTHRBDNM1OPRM1
SCHEMBL3725398 1.00 LMNA (0.42) LMNATSHRTHRBDNM1OPRM1
SCHEMBL7895556 1.00 LMNA (0.42) LMNATSHRTHRBDNM1OPRM1
SCHEMBL28675045 1.00 LMNA (0.42) LMNATSHRTHRBDNM1OPRM1
SCHEMBL30803745 1.00 LMNA (0.42) LMNATSHRTHRBDNM1OPRM1
SCHEMBL29093845 0.95 LMNA (0.39) LMNATSHRTHRBDNM1OPRM1
SCHEMBL2297383 0.95 LMNA (0.39) LMNATSHRTHRBDNM1OPRM1
SCHEMBL5364584 0.95 LMNA (0.39) LMNATSHRTHRBDNM1OPRM1
SCHEMBL1204753 0.95 LMNA (0.39) LMNATSHRTHRBDNM1OPRM1
SCHEMBL7904554 0.90 DNM1 (0.42) LMNATSHRTHRBDNM1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1886143-B1 BIOLOGICAL INDICATOR AMERICAN STERILIZER CO (US) 2014-08-27 EP disclosed
EP-2333548-B1 Biological indicator AMERICAN STERILIZER CO (US) 2014-07-30 EP disclosed
US-8084247-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2011-12-27 US disclosed
US-8039251-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2011-10-18 US disclosed
EP-2333548-A1 Biological indicator American Sterilizer Company (US) 2011-06-15 EP disclosed
US-7960169-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2011-06-14 US disclosed
EP-2325641-A1 Biological indicator American Sterilizer Company (US) 2011-05-25 EP disclosed
US-7741107-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2010-06-22 US disclosed
US-20100151562-A1 Biological indicator AMERICAN STERILIZER COMPANY (US) 2010-06-17 US disclosed
US-20100151563-A1 Biological indicator AMERICAN STERILIZER COMPANY (US) 2010-06-17 US disclosed
US-20100143930-A1 Biological indicator AMERICAN STERILIZER COMPANY (US) 2010-06-10 US disclosed
US-7416883-B2 Biological indicator STERIS INC. (US) 2008-08-26 US disclosed
US-20080199903-A1 Biological indicator STERIS INC. (US) 2008-08-21 US disclosed
US-20060269983-A1 Biological indicator AMERICAN STERILIZER COMPANY 2006-11-30 US disclosed