Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 11/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12047892 | 0.95 | VDR (0.76) | VDRHDAC6HDAC3HDAC2 | |
| SCHEMBL14107839 | 0.89 | VDR (0.77) | VDR | |
| SCHEMBL12047872 | 0.88 | VDR (0.63) | VDRHDAC6HDAC3HDAC2 | |
| SCHEMBL14107838 | 0.86 | VDR (0.78) | VDR | |
| SCHEMBL26322428 | 0.86 | VDR (0.68) | VDRHDAC6HDAC3HDAC2 | |
| SCHEMBL13825086 | 0.84 | VDR (0.72) | VDRHDAC6HDAC3HDAC2 | |
| SCHEMBL12047786 | 0.82 | VDR (0.53) | VDRHDAC6HDAC3HDAC2 | |
| SCHEMBL14356235 | 0.82 | VDR (0.63) | VDR | |
| SCHEMBL14107841 | 0.82 | VDR (0.54) | VDR | |
| SCHEMBL12047912 | 0.82 | VDR (1.00) | VDRHDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110319644-A1 | PROCESS FOR PRODUCTION OF 1-HYDROXY-19-NORCYCLOVITAMIN D DERIVATIVE AND INTERMEDIATE FOR THE PRODUCTION | MERCIAN CORPORATION (JP) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319644-A1 | PROCESS FOR PRODUCTION OF 1-HYDROXY-19-NORCYCLOVITAMIN D DERIVATIVE AND INTERMEDIATE FOR THE PRODUCTION | CYP24A1, CYP27B1, CYP2R1 | VDR 4/4885HDAC6 1576/4885HDAC3 1283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.