Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 7/20 | 0.62 |
| ▸ | FDPS | P14324 | 5/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12060371 | 0.92 | GGPS1 (0.67) | GGPS1FDPSPTPN5LMNAMMP1 | |
| SCHEMBL12048146 | 0.90 | GGPS1 (0.76) | GGPS1FDPSPTPN5LMNAKDM4E | |
| SCHEMBL14199552 | 0.89 | GGPS1 (0.63) | GGPS1FDPSPTPN5LMNAMMP3 | |
| SCHEMBL12048161 | 0.88 | GGPS1 (0.59) | GGPS1FDPSPTPN5 | |
| SCHEMBL12048195 | 0.85 | GGPS1 (0.51) | GGPS1FDPS | |
| SCHEMBL12048208 | 0.85 | GGPS1 (0.59) | GGPS1FDPSLMNAKDM4EALDH1A1 | |
| SCHEMBL12048205 | 0.85 | GGPS1 (0.59) | GGPS1FDPSLMNAMMP2MMP9 | |
| SCHEMBL12048151 | 0.85 | GGPS1 (0.78) | GGPS1FDPSPTPN5LMNA | |
| SCHEMBL12048173 | 0.82 | GGPS1 (0.56) | GGPS1FDPS | |
| SCHEMBL12048201 | 0.82 | GGPS1 (0.55) | GGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071573-B2 | Bisphosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, A BODY CORPORATE AND POLITIC OF THE STATE OF ILLINOIS (US) | 2011-12-06 | — | — | US | disclosed |
| US-7358361-B2 | Biophosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-04-15 | — | — | US | disclosed |