SCHEMBL12052874

O=S(=O)(O)OCCS(=O)(=O)c1ccc(/N=N/c2c(O)c(/N=N/c3ccc(S(=O)(=O)CCOSOOO)cc3)c(O)c(/N=N/c3cc(SOOO)ccc3S(=O)(=O)O)c2O)cc1

nearest known ligand 0.40

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	PTPN11	Q06124	1/20	0.40

▸	THRB	P10828	1/20	0.38

▸	SLC7A11	Q9UPY5	1/20	0.30

▸	CA2	P00918	1/20	0.30

▸	CA3	P07451	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12052511	0.92	THRB (0.39)	PTPN11THRBSLC7A11
SCHEMBL12053113	0.89	PRMT1 (0.36)	PTPN11
SCHEMBL12053231	0.89	PTPN11 (0.41)	PTPN11THRBSLC7A11CA2
SCHEMBL12052533	0.89	THRB (0.37)	PTPN11THRBSLC7A11
SCHEMBL12052532	0.89	THRB (0.37)	PTPN11THRBSLC7A11
SCHEMBL12053099	0.87	THRB (0.40)	PTPN11THRBCA2CA3
SCHEMBL12053031	0.87	THRB (0.36)	PTPN11THRBSLC7A11
SCHEMBL12053035	0.87	THRB (0.36)	PTPN11THRBSLC7A11
SCHEMBL12053154	0.86	PTPN11 (0.39)	PTPN11THRBSLC7A11
SCHEMBL12053206	0.85	PTPN11 (0.39)	PTPN11THRBSLC7A11CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8080101-B2	Azo reactive dyes and mixtures of fiber-reactive azo dyes, their preparation and their use	DYSTAR COLOURS DEUTSCHLAND GMBH (DE)	2011-12-20	—	—	US	disclosed
US-20080295732-A1	Azo Reactive Dyes And Mixtures Of Fiber-Reactive Azo Dyes, Their Preparation And Their Use	DYSTAR TEXTILFARBEN GMBH &CO. DEUTSCHLAND KG (DE)	2008-12-04	—	—	US	disclosed