Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.36 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 4/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.32 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.31 |
| ▸ | BPTF | Q12830 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.31 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12053154 | 0.95 | PTPN11 (0.39) | PTPN11THRBPHLPP2SLC7A11CYP1A2 | |
| SCHEMBL12053231 | 0.94 | PTPN11 (0.41) | PTPN11THRBSLC7A11AMY1ACA1 | |
| SCHEMBL12053253 | 0.89 | PTPN11 (0.43) | PTPN11THRBSLC7A11HSD17B10KDM4E | |
| SCHEMBL12053194 | 0.88 | THRB (0.39) | THRBPHLPP2BRD4BRD3BRD2 | |
| SCHEMBL12052511 | 0.86 | THRB (0.39) | PTPN11THRBPHLPP2SLC7A11CYP1A2 | |
| SCHEMBL12052874 | 0.85 | PTPN11 (0.40) | PTPN11THRBSLC7A11CA2 | |
| SCHEMBL12053326 | 0.85 | PTPN11 (0.37) | PTPN11THRBPHLPP2SLC7A11CYP1A2 | |
| SCHEMBL12052869 | 0.85 | THRB (0.39) | THRBPHLPP2BRD4BRD3BRD2 | |
| SCHEMBL12053192 | 0.83 | BRD4 (0.36) | THRBPHLPP2BRD4CREBBPTP53 | |
| SCHEMBL12053403 | 0.83 | THRB (0.39) | PTPN11THRBPHLPP2SLC7A11BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8080101-B2 | Azo reactive dyes and mixtures of fiber-reactive azo dyes, their preparation and their use | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2011-12-20 | — | — | US | disclosed |
| US-20080295732-A1 | Azo Reactive Dyes And Mixtures Of Fiber-Reactive Azo Dyes, Their Preparation And Their Use | DYSTAR TEXTILFARBEN GMBH &CO. DEUTSCHLAND KG (DE) | 2008-12-04 | — | — | US | disclosed |