Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ATIC | P31939 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.32 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.32 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12053206 | 0.94 | PTPN11 (0.39) | PTPN11THRBP2RX3KDM4EMEN1 | |
| SCHEMBL12053154 | 0.90 | PTPN11 (0.39) | PTPN11THRBMEN1MAPTHPGD | |
| SCHEMBL12053253 | 0.89 | PTPN11 (0.43) | PTPN11THRBP2RX3KDM4EMEN1 | |
| SCHEMBL12052874 | 0.89 | PTPN11 (0.40) | PTPN11THRBSLC7A11CA2 | |
| SCHEMBL12053222 | 0.86 | ATIC (0.36) | PTPN11THRBATICP2RX3KDM4E | |
| SCHEMBL12052511 | 0.86 | THRB (0.39) | PTPN11THRBMEN1MAPTHPGD | |
| SCHEMBL12053326 | 0.84 | PTPN11 (0.37) | PTPN11THRBHSD17B10SLC7A11CA2 | |
| SCHEMBL12052532 | 0.83 | THRB (0.37) | PTPN11THRBMEN1MAPTHPGD | |
| SCHEMBL12052533 | 0.83 | THRB (0.37) | PTPN11THRBMEN1MAPTHPGD | |
| SCHEMBL12053031 | 0.81 | THRB (0.36) | PTPN11THRBSLC7A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8080101-B2 | Azo reactive dyes and mixtures of fiber-reactive azo dyes, their preparation and their use | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2011-12-20 | — | — | US | disclosed |
| US-20080295732-A1 | Azo Reactive Dyes And Mixtures Of Fiber-Reactive Azo Dyes, Their Preparation And Their Use | DYSTAR TEXTILFARBEN GMBH &CO. DEUTSCHLAND KG (DE) | 2008-12-04 | — | — | US | disclosed |