Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12053197 | 0.95 | KDM4E (0.38) | KDM4EMAPTTDP1MEN1KMT2A | |
| SCHEMBL13340930 | 0.93 | KDM4E (0.35) | KDM4EMAPTTDP1MEN1KMT2A | |
| SCHEMBL12053137 | 0.92 | P2RX5 (0.34) | KDM4EMAPTTDP1RAB9AENPP2 | |
| SCHEMBL12053247 | 0.91 | MAPT (0.39) | KDM4EMAPTTDP1MEN1KMT2A | |
| SCHEMBL12053223 | 0.90 | KDM4E (0.41) | KDM4EMAPTTDP1MEN1KMT2A | |
| SCHEMBL12052948 | 0.88 | PRMT1 (0.37) | KDM4EMAPTTDP1MEN1KMT2A | |
| SCHEMBL12052525 | 0.88 | P2RX5 (0.32) | KDM4EMAPTTDP1RAB9AENPP2 | |
| SCHEMBL13340696 | 0.88 | P2RX5 (0.33) | KDM4EMAPTTDP1RAB9AENPP2 | |
| SCHEMBL12053152 | 0.87 | SENP2 (0.32) | KDM4EMAPTTDP1RAB9AALDH1A1 | |
| SCHEMBL12053138 | 0.87 | PHLPP2 (0.39) | MAPTTDP1MEN1KMT2AENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8080101-B2 | Azo reactive dyes and mixtures of fiber-reactive azo dyes, their preparation and their use | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2011-12-20 | — | — | US | disclosed |
| US-20080295732-A1 | Azo Reactive Dyes And Mixtures Of Fiber-Reactive Azo Dyes, Their Preparation And Their Use | DYSTAR TEXTILFARBEN GMBH &CO. DEUTSCHLAND KG (DE) | 2008-12-04 | — | — | US | disclosed |