Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12053140 | 0.93 | KDM4E (0.36) | KDM4EMEN1MAPTKMT2ATDP1 | |
| SCHEMBL12053197 | 0.88 | KDM4E (0.38) | KDM4EMEN1MAPTKMT2ATDP1 | |
| SCHEMBL13340696 | 0.88 | P2RX5 (0.33) | KDM4EMAPTTDP1RAB9AENPP2 | |
| SCHEMBL12053403 | 0.86 | THRB (0.39) | MEN1MAPTKMT2ATDP1ENPP2 | |
| SCHEMBL13340934 | 0.85 | PRMT1 (0.36) | KDM4EMEN1MAPTKMT2ATDP1 | |
| SCHEMBL12053247 | 0.84 | MAPT (0.39) | KDM4EMEN1MAPTKMT2ATDP1 | |
| SCHEMBL12052540 | 0.84 | KDM4E (0.34) | KDM4EMEN1MAPTKMT2ATDP1 | |
| SCHEMBL12053137 | 0.84 | P2RX5 (0.34) | KDM4EMAPTTDP1RAB9AENPP2 | |
| SCHEMBL12053223 | 0.83 | KDM4E (0.41) | KDM4EMEN1MAPTKMT2ATDP1 | |
| SCHEMBL12052554 | 0.82 | MAPT (0.39) | KDM4EMEN1MAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7708786-B2 | Dye mixtures of fiber-reactive azo dyes, their preparation and use | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2010-05-04 | — | — | US | disclosed |
| US-20090025152-A1 | DYE MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND USE | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2009-01-29 | — | — | US | disclosed |
| US-7455699-B2 | Dye mixtures of fiber-reactive azo dyes, their preparation and use | DYSTAR TEXILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2008-11-25 | — | — | US | disclosed |