SCHEMBL12053341

SCHEMBL12053341

CC(=O)Nc1ccc2c(O)c(/N=N/c3ccc4cccc(S(=O)(=O)CCOS(=O)(=O)O)c4c3S(=O)(=O)O)c(SOOO)cc2c1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ PRMT3 O60678 1/20 0.42
▸ EP300 Q09472 1/20 0.42
▸ PRMT6 Q96LA8 1/20 0.42
▸ PRMT1 Q99873 1/20 0.42
▸ ENPP2 Q13822 10/20 0.37
▸ CD40 P25942 1/20 0.37
▸ CD40LG P29965 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.31
▸ CYP1A2 P05177 1/20 0.31
▸ HIF1A Q16665 1/20 0.31
▸ MPL P40238 1/20 0.31
▸ CTRC Q99895 1/20 0.31
▸ CA2 P00918 1/20 0.30
▸ CA3 P07451 1/20 0.30
▸ PHLPP2 Q6ZVD8 1/20 0.30
▸ PTPN11 Q06124 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14388948 0.88 PRMT3 (0.54) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL13995000 0.81 PRMT3 (0.55) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL13880641 0.78 PRMT3 (0.53) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL13949157 0.77 FUT8 (0.41) PRMT1ENPP2CD40CD40LGALDH1A1
SCHEMBL13949165 0.76 ENPP2 (0.33) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL12053327 0.75 PRMT1 (0.47) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL14362773 0.75 PRMT1 (0.50) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL13046146 0.73 PRMT1 (0.79) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL13538879 0.72 FUT8 (0.53) PRMT1ENPP2ALDH1A1CYP1A2HIF1A
SCHEMBL14355349 0.72 ALDH1A1 (0.42) ENPP2ALDH1A1CYP1A2HIF1AMPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8080101-B2 Azo reactive dyes and mixtures of fiber-reactive azo dyes, their preparation and their use DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2011-12-20 — — US disclosed
US-7708786-B2 Dye mixtures of fiber-reactive azo dyes, their preparation and use DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2010-05-04 — — US disclosed
US-20090025152-A1 DYE MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND USE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2009-01-29 — — US disclosed
US-20080295732-A1 Azo Reactive Dyes And Mixtures Of Fiber-Reactive Azo Dyes, Their Preparation And Their Use DYSTAR TEXTILFARBEN GMBH &CO. DEUTSCHLAND KG (DE) 2008-12-04 — — US disclosed
US-7455699-B2 Dye mixtures of fiber-reactive azo dyes, their preparation and use DYSTAR TEXILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2008-11-25 — — US disclosed
US-20070271711-A1 Dye Mixtures of Fibre-Reactive Azo Dyes Production and Use Thereof DYSTAR TEXTILFARBEN GMBH & CO., DEUTSCHLAND KG (DE) 2007-11-29 — — US disclosed
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