Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 14/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1206214 | 1.00 | ADRB2 (0.52) | ADRB2EPHX2MAPTALDH1A1HPGD | |
| SCHEMBL2824703 | 0.86 | ADRB2 (0.47) | ADRB2ADRB3ADRB1ADRA2AADRA2B | |
| SCHEMBL2824699 | 0.86 | ADRB2 (0.47) | ADRB2ADRB3ADRB1ADRA2AADRA2B | |
| SCHEMBL1206030 | 0.86 | ADRB2 (0.47) | ADRB2ADRB3ADRB1ADRA2AADRA2B | |
| SCHEMBL1206028 | 0.86 | ADRB2 (0.47) | ADRB2ADRB3ADRB1ADRA2AADRA2B | |
| SCHEMBL2746443 | 0.82 | ADRB2 (0.44) | ADRB2ALDH1A1NPSR1ADRB3ADRB1 | |
| SCHEMBL1205434 | 0.82 | ADRB2 (0.46) | ADRB2ADRB3ADRB1ADRA2AADRA2B | |
| SCHEMBL1205430 | 0.82 | ADRB2 (0.46) | ADRB2ADRB3ADRB1ADRA2AADRA2B | |
| SCHEMBL1204324 | 0.81 | ADRB2 (0.52) | ADRB2MAPTADRB3ADRB1ADRA2A | |
| SCHEMBL1204325 | 0.81 | ADRB2 (0.52) | ADRB2MAPTADRB3ADRB1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028442-A1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXYETHYL) PHENOL AS AGONISTS OF THE BETA2 ADRENERGIC RECEPTOR | ALMIRALL, S.A. (ES) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028442-A1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXYETHYL) PHENOL AS AGONISTS OF THE BETA2 ADRENERGIC RECEPTOR | ADRB2, ADRB1, ADRA2C | ADRB2 1/4885EPHX2 576/4885MAPT 2590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.