SCHEMBL1206258

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1206294	0.77	ADORA3 (0.47)	ADORA3HTTNPC1RAB9ATMIGD3
	SCHEMBL18666640	0.76	RAB9A (0.52)	ADORA3HTTNPC1RAB9A
	SCHEMBL6434738	0.75	ADORA3 (0.55)	ADORA3NPC1RAB9AATM
	SCHEMBL1206235	0.75	ADORA3 (0.55)	ADORA3NPC1RAB9AATMTMIGD3
	SCHEMBL6439071	0.74	ADORA3 (0.54)	ADORA3MAPTNPC1RAB9A
	SCHEMBL1204620	0.74	ADORA3 (0.54)	ADORA3HTTNPC1RAB9ATMIGD3
	SCHEMBL5874038	0.73	ADORA3 (0.62)	ADORA3HTTNPC1RAB9ATMIGD3
	SCHEMBL6435371	0.72	ADORA3 (0.52)	ADORA3HTTNPC1RAB9ATMIGD3
	SCHEMBL6435363	0.72	CSF1R (0.53)	ADORA3HTTNPC1RAB9ATMIGD3
	SCHEMBL6435943	0.71	ADORA3 (0.51)	ADORA3HTTNPC1RAB9ATMIGD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.