SCHEMBL12065629

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12065628	0.90	MLKL (0.47)	MLKLNPC1RAB9APKMPDE10A
	SCHEMBL12066600	0.88	SCN10A (0.45)	MLKLSCN10ANPC1RAB9APKM
	SCHEMBL12065623	0.88	PRCP (0.43)	MLKLSCN10ANPC1RAB9APKM
	SCHEMBL14770666	0.86	MLKL (0.59)	MLKLSCN10ANPC1RAB9APKM
	SCHEMBL14770699	0.86	MLKL (0.46)	MLKLSCN10ANPC1RAB9APKM
	SCHEMBL12065632	0.84	MLKL (0.46)	MLKLSCN10ANPC1RAB9APKM
	SCHEMBL14770709	0.82	MEN1 (0.48)	MLKLSCN10ARAB9AMEN1KMT2A
	SCHEMBL12066586	0.82	SCN10A (0.44)	MLKLSCN10APDE10AMEN1KMT2A
	SCHEMBL12065613	0.82	ALPL (0.47)	MLKLSCN10AIGFBP3PDE2A
	SCHEMBL12066573	0.82	SCN10A (0.46)	MLKLSCN10APDE10AKMT2APDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.