Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 10/20 | 0.69 |
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MYD88 | Q99836 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9980413 | 0.83 | MEN1 (0.45) | LMNAMAPTSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL12067909 | 0.81 | MAPT (0.70) | LMNAMAPTSMN1; SMN2PKMMAPK1 | |
| SCHEMBL9980456 | 0.80 | MAPT (0.77) | LMNAMAPTSMN1; SMN2PKMMAPK1 | |
| SCHEMBL1804544 | 0.79 | MAPT (0.79) | LMNAMAPTSMN1; SMN2PKMMAPK1 | |
| SCHEMBL12065803 | 0.75 | MAPT (0.68) | LMNAMAPTSMN1; SMN2PKMMAPK1 | |
| SCHEMBL12066385 | 0.75 | MAPT (0.72) | LMNAMAPTSMN1; SMN2PKMMAPK1 | |
| SCHEMBL12067935 | 0.75 | MAPT (0.67) | LMNAMAPTSMN1; SMN2PKMMAPK1 | |
| SCHEMBL3620493 | 0.72 | LMNA (0.78) | LMNAMAPTSMN1; SMN2PKMMAPK1 | |
| SCHEMBL12067109 | 0.72 | LMNA (0.61) | LMNAMAPTSMN1; SMN2PKMMAPK1 | |
| SCHEMBL9980389 | 0.70 | MAPT (0.69) | LMNAMAPTSMN1; SMN2PKMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | disclosed |