SCHEMBL12066656

SCHEMBL12066656

Cc1c2nc(cc3ccc([nH]3)c(-c3cc(OCCC[N+](C)(C)C)cc(OCCC[N+](C)(C)C)c3)c3nc(cc4ccc1[nH]4)C=C3)C=C2

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.48
▸ STAT1 P42224 1/20 0.48
▸ PPARG P37231 1/20 0.30
▸ PPARA Q07869 1/20 0.30
▸ TERT O14746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL584793 0.89 STAT3 (0.52) STAT3STAT1PPARGPPARATERT
Hydrochloric Acid SCHEMBL584374 0.88 STAT3 (0.51) STAT3STAT1PPARGPPARATERT
Hydrochloric Acid SCHEMBL29883333 0.88 STAT3 (0.51) STAT3STAT1PPARGPPARATERT
Exeporfinium SCHEMBL585997 0.88 STAT3 (0.52) STAT3STAT1TERT
Exeporfinium SCHEMBL584418 0.87 STAT3 (0.51) STAT3STAT1TERT
Exeporfinium SCHEMBL5012396 0.87 STAT3 (0.51) STAT3STAT1TERT
SCHEMBL585880 0.86 STAT3 (0.41) STAT3STAT1
Hydrochloric Acid SCHEMBL583840 0.85 STAT3 (0.40) STAT3STAT1TERT
SCHEMBL10084843 0.85 STAT3 (0.40) STAT3STAT1
Hydrochloric Acid SCHEMBL29648896 0.85 STAT3 (0.48) STAT3STAT1TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8084602-B2 Porphyrin derivatives and their use in photodynamic therapy DESTINY PHARMA LIMITED (CH) 2011-12-27 — — US disclosed
US-20070281915-A1 Porphyrin Derivatives and Their Use in Photodynamic Therapy DESTINY PHARMA LIMITED 2007-12-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070281915-A1 Porphyrin Derivatives and Their Use in Photodynamic Therapy PPOX, PPIF, TYR STAT3 2340/4885STAT1 1254/4885PPARG 930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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