Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.34 |
| ▸ | KRAS | P01116 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22096276 | 0.84 | POLRMT (0.33) | POLRMTKRASRIPK1 | |
| SCHEMBL12068858 | 0.83 | POLRMT (0.32) | POLRMT | |
| SCHEMBL10119994 | 0.82 | CYP3A4 (0.45) | POLRMT | |
| SCHEMBL14845671 | 0.82 | TMPRSS2 (0.33) | — | |
| SCHEMBL10142401 | 0.82 | TMPRSS2 (0.33) | — | |
| SCHEMBL22096272 | 0.82 | POLRMT (0.33) | POLRMTKRAS | |
| SCHEMBL14845682 | 0.82 | TMPRSS2 (0.33) | — | |
| SCHEMBL22096270 | 0.81 | TMPRSS2 (0.44) | POLRMTKRASRIPK1 | |
| SCHEMBL23818574 | 0.81 | POLRMT (0.44) | POLRMTRIPK1 | |
| SCHEMBL12066945 | 0.80 | CYP3A4 (0.33) | POLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011150288-A1 | 1'-SUBSTITUTED-CARBA-NUCLEOSIDE PRODRUGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2011-12-01 | — | — | WO | disclosed |