Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.89 |
| ▸ | CA4 | P22748 | 2/20 | 0.89 |
| ▸ | CES1 | P23141 | 3/20 | 0.55 |
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 11/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL28061734 | 0.97 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL27817276 | 0.97 | CA2 (0.94) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL28186111 | 0.97 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL17102796 | 0.97 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL10898907 | 0.97 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL11789341 | 0.97 | CA2 (0.94) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL944537 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL29624 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL1445056 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL20570232 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6709 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118160922-B | Preparation method of high-bioavailability yellow beta-carotene powder | 万华化学集团股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122037206-A | Bio-based polyol, preparation method, foam composition, foam and refrigeration device | TCL家用电器（合肥）有限公司 | 2026-05-15 | — | — | CN | claimed |
| EP-3570977-B1 | A PROCESS FOR PREPARING A MOLDING COMPRISING ZINC AND A TITANIUM-CONTAINING ZEOLITE | BASF SE (DE) | 2026-04-08 | — | — | EP | claimed |
| WO-2025242659-A1 | ADDITIVE COMPOSITION FOR AUTOMATIC DISHWASHING | RECKITT BENCKISER FINISH B.V. (NL) | 2025-11-27 | — | — | WO | claimed |
| EP-4631999-A1 | POLYALKYLENE CARBONATE RESIN COMPOSITION AND PREPARATION METHOD THEREFOR | LG CHEM, LTD. (KR) | 2025-10-15 | — | — | EP | claimed |
| US-20250250386-A1 | PRODUCTION OF POLYURETHANE OR POLYISOCYANURATE FOAM | EVONIK OPERATIONS GMBH (DE) | 2025-08-07 | — | — | US | claimed |
| US-20250250385-A1 | PRODUCTION OF POLYURETHANE OR POLYISOCYANURATE FOAM | EVONIK OPERATIONS GMBH (DE) | 2025-08-07 | — | — | US | claimed |
| US-12343701-B2 | Superabsorbent polymer and preparation method thereof | LG CHEM, LTD. (KR) | 2025-07-01 | — | — | US | claimed |
| WO-2025128922-A1 | SYNERGISTIC ANTIMICROBIAL COMPOSITIONS COMPRISING A PHENOLIC EXTRACT FROM ALGAE | LANXESS CORPORATION (US) | 2025-06-19 | — | — | WO | claimed |
| WO-2025121791-A1 | POLYALKYLENE CARBONATE-BASED RESIN AND METHOD FOR PRODUCING SAME | 주식회사 엘지화학 | 2025-06-12 | — | — | WO | claimed |
| EP-0223515-A2 | Oral compositions comprising salicylamides and zinc salts for the synergistic inhibition of dental plaque | UNILEVER PLC (GB) | 1987-05-27 | — | — | EP | claimed |
| US-4647452-A | Oral compositions of salicylamides and zinc salts for the synergistic inhibition of dental plaque | LEVER BROTHERS COMPANY (US) | 1987-03-03 | — | — | US | claimed |
| EP-0109102-A2 | Storage stable topical pharmaceutical composition including nitrogen-containing stabilizers | THE PROCTER & GAMBLE COMPANY (US) | 1984-05-23 | — | — | EP | claimed |
| US-4263451-A | OXIDATION, FILTRATION | PHILLIPS PETROLEUM COMPANY (US) | 1981-04-21 | — | — | US | claimed |
| US-4261982-A | ZINC ERYTHROMYCIN FOR ACNE | THE PROCTER & GAMBLE COMPANY (US) | 1981-04-14 | — | — | US | claimed |
| US-4230885-A | DISPROPORTIONATION | PHILLIPS PETROLEUM COMPANY (US) | 1980-10-28 | — | — | US | claimed |
| US-4192794-A | Titanium dioxide-pigmented polymer compositions having improved visible and ultraviolet light stability | EASTMAN KODAK COMPANY (US) | 1980-03-11 | — | — | US | claimed |
| US-4192810-A | Preparation of vicinal epoxides | PHILLIPS PETROLEUM COMPANY (US) | 1980-03-11 | — | — | US | claimed |
| US-4100269-A | ZINC COMPOUND | LEVER BROTHERS COMPANY (US) | 1978-07-11 | — | — | US | claimed |
| US-4022880-A | ZINC IONS, 3,4,5-TRIBROMO-SALICYLANILIDE, QUATERNARY AMMONIUM COMPOUNDS | LEVER BROTHERS COMPANY (US) | 1977-05-10 | — | — | US | claimed |