Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.57 |
| ▸ | DRD2 | P14416 | 8/20 | 0.56 |
| ▸ | DRD4 | P21917 | 7/20 | 0.56 |
| ▸ | DRD3 | P35462 | 7/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 3/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2710149 | 0.86 | ACHE (0.57) | ACHEDRD2DRD4DRD3MEN1 | |
| SCHEMBL169363 | 0.82 | DRD2 (0.60) | ACHEDRD2DRD4DRD3POLB | |
| SCHEMBL2636257 | 0.79 | ACHE (0.50) | ACHEDRD2DRD4DRD3MEN1 | |
| SCHEMBL5633507 | 0.79 | ACHE (0.54) | ACHEDRD2DRD4DRD3POLB | |
| SCHEMBL2636668 | 0.79 | MEN1 (0.53) | ACHEDRD2DRD4DRD3MEN1 | |
| SCHEMBL2636322 | 0.78 | BCHE (0.53) | ACHEDRD2DRD4DRD3POLB | |
| SCHEMBL11453030 | 0.78 | POLB (0.67) | ACHEDRD2DRD4DRD3POLB | |
| SCHEMBL1740324 | 0.78 | CYP2D6 (0.52) | ACHEDRD2DRD4DRD3MEN1 | |
| SCHEMBL6981484 | 0.76 | DRD2 (0.58) | ACHEDRD2DRD4DRD3POLB | |
| SCHEMBL4687045 | 0.75 | ACHE (0.59) | ACHEDRD2DRD4DRD3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011148922-A1 | NOVEL QUINAZOLINE COMPOUND | 田辺三菱製薬株式会社 (JP) | 2011-12-01 | — | — | WO | disclosed |