Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 15/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1009815 | 0.85 | MTNR1A (0.75) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL14927052 | 0.81 | MTNR1A (0.61) | MTNR1AMTNR1B | |
| SCHEMBL19710702 | 0.77 | MTNR1A (0.47) | MTNR1AMTNR1B | |
| SCHEMBL14907347 | 0.76 | MTNR1A (0.73) | MTNR1AMTNR1BHTR2B | |
| SCHEMBL17150039 | 0.76 | CA12 (0.61) | MTNR1AMTNR1B | |
| SCHEMBL1010724 | 0.75 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL18183555 | 0.75 | CA12 (0.60) | MTNR1AMTNR1B | |
| SCHEMBL16437111 | 0.74 | TSHR (0.53) | MTNR1AMTNR1B | |
| SCHEMBL19612412 | 0.74 | SMN1; SMN2 (0.55) | — | |
| SCHEMBL13178649 | 0.73 | CNR2 (0.60) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933096-B2 | Antimicrobial agents | Rugers, The State University of New Jersey (US) | 2015-01-13 | — | — | US | disclosed |
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2013-05-09 | — | — | US | disclosed |
| WO-2011159926-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-12-22 | — | — | WO | disclosed |
| WO-2011156626-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | MRPL21, ARG1, RPP30 | MTNR1A 1415/4885MTNR1B 1904/4885HTR2C 4829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.