SCHEMBL1896934

SCHEMBL1896934

C#CCN(CC(=O)O)C(=O)OC(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA14 Q9ULX7 1/20 0.35
KCNQ4 P56696 1/20 0.33
KCNQ5 Q9NR82 1/20 0.33
HDAC1 Q13547 2/20 0.32
HDAC2 Q92769 2/20 0.32
HDAC6 Q9UBN7 2/20 0.32
HDAC3 O15379 1/20 0.30
NCOR2 Q9Y618 1/20 0.30
CTSD P07339 1/20 0.30
CTSL P07711 1/20 0.30
CTSB P07858 1/20 0.30
CTSS P25774 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1207293 0.87 CA14 (0.39) CA14KCNQ4KCNQ5HDAC1HDAC2
SCHEMBL1688918 0.86 CA14 (0.35) CA14KCNQ4KCNQ5HDAC1HDAC2
SCHEMBL20029121 0.85 CA14 (0.34) CA14KCNQ4KCNQ5HDAC1HDAC2
SCHEMBL3174629 0.83 CA14 (0.36) CA14KCNQ4KCNQ5HDAC1HDAC2
SCHEMBL18829734 0.83 CA14 (0.36) CA14HDAC1HDAC2HDAC6
SCHEMBL78691 0.83 CA14 (0.41) CA14HDAC1HDAC2HDAC6HDAC3
SCHEMBL3530471 0.82 CA14 (0.36) CA14KCNQ4KCNQ5HDAC1HDAC2
SCHEMBL7421637 0.81 CTSK (0.35) CA14HDAC1HDAC2HDAC6
SCHEMBL3177412 0.81 KCNQ4 (0.36) CA14KCNQ4KCNQ5HDAC1HDAC2
SCHEMBL15481109 0.80 CA14 (0.33) CA14HDAC1HDAC2HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137643-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL SOC DES PRODUITS NESTLE S A (CH) 2026-05-21 US claimed
US-12539288-B2 Compositions and methods using at least one glycine or derivative thereof and/or at least one N-acetylcysteine or derivative thereof, and at least one thymol and/or carvacrol SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-02-03 US claimed
US-20250281438-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL SOCIETE DES PRODUITS NESTLE S.A. (CH) 2025-09-11 US claimed
US-11974975-B2 Compositions and methods using at least one glycine or derivative thereof, at least one N-acetylcysteine or derivative thereof, and at least one nicotinamide riboside or NAD+ precursor SOCIETE DES PRODUITS NESTLE S.A. (CH) 2024-05-07 US claimed
US-20240100006-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND AT LEAST ONE LARGE NEUTRAL AMINO ACID AND/OR CATIONIC AMINO ACID OR PRECURSOR THEREOF SOCIETE DES PRODUITS NESTLE S.A. (CH) 2024-03-28 US claimed
US-20240091186-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF, AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE NICOTINAMIDE RIBOSIDE OR NAD+ PRECURSOR SOCIETE DES PRODUITS NESTLE S.A. (CH) 2024-03-21 US claimed
EP-4262776-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL Société des Produits Nestlé S.A. (CH) 2023-10-25 EP claimed
US-11730711-B2 Benefits of supplementation with n-acetylcysteine and glycine to improve glutathione levels BAYLOR COLLEGE OF MEDICINE (US) 2023-08-22 US claimed
US-20230172232-A1 COMPOSITIONS AND METHODS USING AN AMINO ACID BLEND FOR PROVIDING A HEALTH BENEFIT IN AN ANIMAL Société des Produits Nestlé S.A. (CH) 2023-06-08 US claimed
WO-2022128870-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL Société des Produits Nestlé S.A. (CH) 2022-06-23 WO claimed
US-20210244696-A1 BENEFITS OF SUPPLEMENTATION WITH N-ACETYLCYSTEINE AND GLYCINE TO IMPROVE GLUTATHIONE LEVELS BAYLOR COLLEGE OF MEDICINE 2021-08-12 US claimed
EP-3855943-A2 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF, AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE NICOTINAMIDE RIBOSIDE OR NAD+ PRECURSOR Société des Produits Nestlé S.A. (CH) 2021-08-04 EP claimed
CN-112654264-A Using at least one glycine or derivative thereof, at least one N-acetylcysteine or derivative thereof, and at least one nicotinamide riboside or NAD+Composition and method of precursors 雀巢产品有限公司 2021-04-13 CN claimed
US-10952982-B2 Benefits of supplementation with N-acetylcysteine and glycine to improve glutathione levels SOCIETE DES PRODUITS NESTLE S.A. (CH) 2021-03-23 US claimed
CN-112028916-A Programmed cell death protein receptor-1 targeted molecular probe and preparation 江苏省原子医学研究所 2020-12-04 CN claimed
WO-2020064946-A2 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF, AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE NICOTINAMIDE RIBOSIDE OR NAD+ PRECURSOR Société des Produits Nestlé S.A. (CH) 2020-04-02 WO claimed
US-20180161297-A1 BENEFITS OF SUPPLEMENTATION WITH N-ACETYLCYSTEINE AND GLYCINE TO IMPROVE GLUTATHIONE LEVELS Société des Produits Nestlé S.A. (CH) 2018-06-14 US claimed
US-5665598-A Synthesis of chiral N-protected-α-substituted-glycine free acids by zinc-mediated addition of organic halide to glycine cation equivalent G. D. SEARLE & CO. (US) 1997-09-09 US claimed
EP-0755379-A1 SYNTHESIS N-PROTECTED AMINO ACIDS, ESPECIALLY N-BOC-L-PROPARGYLGLYCINE BY ZINC-MEDIATED ADDITION OR ORGANIC HALIDES TO GLYCINE CATION EQUIVALENT G.D. SEARLE & CO. (US) 1997-01-29 EP claimed
WO-1995028385-A1 SYNTHESIS N-PROTECTED AMINO ACIDS, ESPECIALLY N-BOC-L-PROPARGYLGLYCINE BY ZINC-MEDIATED ADDITION OR ORGANIC HALIDES TO GLYCINE CATION EQUIVALENT G.D. SEARLE & CO. (US) 1995-10-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539288-B2 Compositions and methods using at least one glycine or derivative thereof and/or at least one N-acetylcysteine or derivative thereof, and at least one thymol and/or carvacrol LIPC, GGT1, TGM2 CA14 2395/4885KCNQ4 4600/4885KCNQ5 4749/4885
US-20260137643-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL LIPC, GGT1, TGM2 CA14 2129/4885KCNQ4 4596/4885KCNQ5 4782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.