Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.32 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641389 | 0.86 | CA14 (0.36) | DPP4RAB9AALDH1A1CA14L3MBTL1 | |
| SCHEMBL8641383 | 0.86 | CA14 (0.36) | DPP4RAB9AALDH1A1CA14L3MBTL1 | |
| SCHEMBL1207293 | 0.84 | CA14 (0.39) | CA14HDAC6KCNQ4KCNQ5HDAC1 | |
| SCHEMBL956549 | 0.84 | ALDH1A1 (0.42) | DPP4ALDH1A1CA14HDAC6HDAC1 | |
| SCHEMBL18306605 | 0.84 | DPP4 (0.56) | DPP4ALDH1A1CA14HDAC6 | |
| SCHEMBL12492869 | 0.83 | DPP4 (0.38) | DPP4ALDH1A1SLC6A2SLC6A4CA14 | |
| SCHEMBL25166477 | 0.80 | DPP4 (0.35) | DPP4 | |
| SCHEMBL3178526 | 0.80 | ALDH1A1 (0.38) | DPP4ALDH1A1SLC6A2SLC6A4CA14 | |
| SCHEMBL3530471 | 0.80 | CA14 (0.36) | DPP4SLC6A2SLC6A4CA14HDAC6 | |
| SCHEMBL4866631 | 0.79 | DPP4 (0.36) | DPP4ALDH1A1CA14L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118240486-A | Composite repairing and reinforcing material for oil and gas pipeline, preparation method and application | 中国石油天然气集团有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-118240486-A | Composite repairing and reinforcing material for oil and gas pipeline, preparation method and application | 中国石油天然气集团有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-106068262-B | Quinazoline derivant and preparation method thereof and application in medicine | HAISCO PHARMACEUTICAL GROUP INC. (CN) | 2019-10-29 | — | — | CN | disclosed |
| US-20190194194-A1 | ANTIBACTERIAL CYCLOPENTA[C]PYRROLE SUBSTITUTED 3,4-DIHYDRO-1H-[1,8]NAPHTHYRIDINONES | Janssen Sciences Ireland Unlimited Company (IE) | 2019-06-27 | — | — | US | disclosed |
| US-20190084982-A1 | ANTIBACTERIAL CYCLOPENTA[C]PYRROLE SUBSTITUTED 3,4-DIHYDRO-1H-[1,8]NAPHTHYRIDINONES | Janssen Sciences Ireland Unlimited Company (IE) | 2019-03-21 | — | — | US | disclosed |
| EP-2742045-B1 | ANTIBACTERIAL CYCLOPENTA[C]PYRROLE SUBSTITUTED 3,4-DIHYDRO-1H-[1,8]NAPHTHYRIDINONES | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2019-01-23 | — | — | EP | disclosed |
| CN-105085530-B | Ternary condenses cyclosubstituted amino hexatomic ring analog derivative and its application in medicine | 四川海思科制药有限公司 | 2019-01-04 | — | — | CN | disclosed |
| US-10155759-B2 | Antibacterial cyclopenta[c]pyrrole substituted 3,4-dihydro-1H-[1,8]naphthyridinones | JANSSEN SCIENCES IRELAND UC (IE) | 2018-12-18 | — | — | US | disclosed |
| US-20180105525-A1 | ANTIBACTERIAL CYCLOPENTA[C]PYRROLE SUBSTITUTED 3,4-DIHYDRO-1H-[1,8]NAPHTHYRIDINONES | Janssen Sciences Ireland Unlimited Company (IE) | 2018-04-19 | — | — | US | disclosed |
| US-9884864-B2 | Antibacterial cyclopenta[C]pyrrole substituted 3,4-Dihydro-1H-[1,8]naphthyridinones | JANSSEN SCIENCES IRELAND UC (IE) | 2018-02-06 | — | — | US | disclosed |
| US-20050227960-A1 | Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY | 2005-10-13 | — | — | US | disclosed |
| US-20050192276-A1 | Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY | 2005-09-01 | — | — | US | disclosed |
| WO-2005079496-A2 | SUBSTITUTED BICYCLOALKYLAMINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-09-01 | — | — | WO | disclosed |
| WO-2005079519-A2 | SUBSTITUTED BICYCLOALKYLAMINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-09-01 | — | — | WO | disclosed |
| EP-1539733-A2 | AZABICYCLIC COMPOUNDS ARE CENTRAL NERVOUS SYSTEM ACTIVE AGENTS | Abbott Laboratories (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20040152724-A1 | Azabicyclic compounds are central nervous system active agents | ABBVIE INC. | 2004-08-05 | — | — | US | disclosed |
| US-20040044029-A1 | Azabicyclic compounds are central nervous system active agents | ABBOTT LABORATORIES | 2004-03-04 | — | — | US | disclosed |
| WO-2004016604-A2 | AZABICYCLIC COMPOUNDS ARE CENTRAL NERVOUS SYSTEM ACTIVE AGENTS | ABBOTT LABORATORIES (US) | 2004-02-26 | — | — | WO | disclosed |
| US-6156752-A | Optically active 1,4-dihydropyridine compounds as bradykinin antagonists | PFIZER INC (US) | 2000-12-05 | — | — | US | disclosed |
| EP-0899261-A1 | Optical active 1,4-dihydropyridine compounds as bradykinin antagonists | PFIZER INC. (US) | 1999-03-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192276-A1 | Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity | CCR1, CCR2, BDKRB1 | DPP4 3375/4885RAB9A 1173/4885ALDH1A1 2875/4885 |
| US-20040152724-A1 | Azabicyclic compounds are central nervous system active agents | ACHE, CHRNA6, CHRNA2 | DPP4 4015/4885RAB9A 2352/4885ALDH1A1 123/4885 |
| US-20040044029-A1 | Azabicyclic compounds are central nervous system active agents | ACHE, CHRNA6, CHRNA2 | DPP4 4015/4885RAB9A 2352/4885ALDH1A1 123/4885 |
| US-20190084982-A1 | ANTIBACTERIAL CYCLOPENTA[C]PYRROLE SUBSTITUTED 3,4-DIHYDRO-1H-[1,8]NAPHTHYRIDINONES | ECI1, ALPI, PREP | DPP4 529/4885RAB9A 1872/4885ALDH1A1 965/4885 |
| US-20190194194-A1 | ANTIBACTERIAL CYCLOPENTA[C]PYRROLE SUBSTITUTED 3,4-DIHYDRO-1H-[1,8]NAPHTHYRIDINONES | ECI1, ALPI, PREP | DPP4 529/4885RAB9A 1872/4885ALDH1A1 965/4885 |
| US-20050227960-A1 | Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity | CCR1, CCR2, CCR10 | DPP4 2937/4885RAB9A 1127/4885ALDH1A1 1969/4885 |
| US-20180105525-A1 | ANTIBACTERIAL CYCLOPENTA[C]PYRROLE SUBSTITUTED 3,4-DIHYDRO-1H-[1,8]NAPHTHYRIDINONES | ECI1, ALPI, PREP | DPP4 529/4885RAB9A 1872/4885ALDH1A1 965/4885 |
| US-10155759-B2 | Antibacterial cyclopenta[c]pyrrole substituted 3,4-dihydro-1H-[1,8]naphthyridinones | ECI1, ALPI, PREP | DPP4 529/4885RAB9A 1872/4885ALDH1A1 965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.