SCHEMBL120740

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30434895	1.00	GSK3B (0.50)	GSK3BBRD4IL17AKDM4EALDH1A1
	SCHEMBL121941	0.90	TNKS (0.44)	GSK3BBRD4IL17AHDAC3HDAC1
	SCHEMBL30434653	0.90	TNKS (0.44)	GSK3BBRD4IL17AHDAC3HDAC1
	SCHEMBL145971	0.87	GSK3B (0.44)	GSK3BBRD4IL17AKDM4EALDH1A1
	SCHEMBL30434069	0.87	GSK3B (0.64)	GSK3BBRD4KDM4EALDH1A1MAPT
	SCHEMBL146847	0.87	GSK3B (0.64)	GSK3BBRD4KDM4EALDH1A1MAPT
	SCHEMBL378321	0.83	TNKS (0.50)	GSK3BKDM4EALDH1A1MAPTFGFR1
	SCHEMBL348771	0.78	PARP1 (0.48)	BRD4IL17AHDAC3HDAC1HDAC2
	SCHEMBL346585	0.78	TNKS (0.48)	BRD4IL17AMAPTHDAC3HDAC1
	SCHEMBL146053	0.78	BRD4 (0.54)	BRD4IL17AKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.