SCHEMBL146847

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30434069	1.00	GSK3B (0.64)	GSK3BIDO1TDO2IDO2FGFR1
	SCHEMBL148677	0.89	GSK3B (0.51)	GSK3BIDO1TDO2IDO2HDAC3
	SCHEMBL30434521	0.89	GSK3B (0.51)	GSK3BIDO1TDO2IDO2HDAC3
	SCHEMBL378321	0.89	TNKS (0.50)	GSK3BIDO1TDO2IDO2FGFR1
	SCHEMBL30434895	0.87	GSK3B (0.50)	GSK3BIDO1TDO2IDO2FGFR1
	SCHEMBL120740	0.87	GSK3B (0.50)	GSK3BIDO1TDO2IDO2FGFR1
	SCHEMBL18643635	0.81	HTR1A (0.55)	GSK3BIDO1TDO2IDO2FGFR1
	SCHEMBL145971	0.80	GSK3B (0.44)	GSK3BIDO1TDO2IDO2FGFR1
	SCHEMBL121937	0.80	TNKS (0.48)	GSK3BTNKSPARP1TNKS2KDM4E
	SCHEMBL3534889	0.78	GSK3B (1.00)	GSK3BIDO1TDO2IDO2FGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.