Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.53 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23660644 | 0.82 | STK17B (0.52) | STK17BSTK17ATDP1LMNADRD2 | |
| SCHEMBL24799132 | 0.81 | STK17B (0.46) | STK17BSTK17ALMNAMEN1KMT2A | |
| SCHEMBL14830020 | 0.81 | PYGL (0.53) | STK17BSTK17ATDP1SMN1; SMN2CA1 | |
| SCHEMBL12240462 | 0.79 | STK17B (0.44) | STK17BSTK17ATDP1MAOAMAOB | |
| SCHEMBL21077910 | 0.79 | DRD2 (0.55) | STK17BSTK17ATDP1IDO1LMNA | |
| SCHEMBL15862589 | 0.78 | STK17B (0.43) | STK17BSTK17ATDP1MEN1KMT2A | |
| SCHEMBL9998914 | 0.78 | STK17B (0.41) | STK17BSTK17AIDO1LMNAMEN1 | |
| SCHEMBL9998916 | 0.78 | STK17B (0.41) | STK17BSTK17AIDO1LMNAMEN1 | |
| SCHEMBL9999462 | 0.78 | STK17B (0.41) | STK17BSTK17AIDO1LMNAMEN1 | |
| SCHEMBL15862588 | 0.77 | STK17B (0.42) | STK17BSTK17ATDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011162409-A1 | COMPOUNDS HAVING TRPV1 ANTAGONISTIC ACTIVITY AND USES THEREOF | SHIONOGI & CO., LTD. (JP) | 2011-12-29 | — | — | WO | disclosed |