Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 5/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MASP2 | O00187 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14083 | 0.89 | CHRM2 (0.44) | LMNAIDO1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL19571325 | 0.88 | MEN1 (0.43) | ANPEPERAP2L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL20124146 | 0.86 | ANPEP (0.37) | LMNAANPEPERAP2ALDH1A1MASP2 | |
| SCHEMBL11981656 | 0.86 | ANPEP (0.50) | ANPEPPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL11774 | 0.85 | ANPEP (0.56) | LMNAANPEPERAP2RAB9AMEN1 | |
| SCHEMBL11981551 | 0.84 | BCHE (0.43) | LMNAIDO1L3MBTL1ALDH1A1 | |
| SCHEMBL11981710 | 0.84 | LMNA (0.42) | LMNAIDO1ANPEPERAP2L3MBTL1 | |
| SCHEMBL11981716 | 0.83 | LMNA (0.45) | LMNAIDO1ANPEPERAP2L3MBTL1 | |
| SCHEMBL11981491 | 0.83 | IDO1 (0.52) | LMNAIDO1L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL11981601 | 0.81 | LMNA (0.42) | LMNAIDO1ANPEPERAP2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120220566-A1 | Antimicrobial Compounds and Methods of Making and Using the Same | RIB-X PHARMACEUTICALS, INC. (US) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220566-A1 | Antimicrobial Compounds and Methods of Making and Using the Same | MPO, LPO, CAT | LMNA 2222/4885IDO1 1215/4885ANPEP 653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.