Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | UQCRB | P14927 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20082475 | 0.85 | ALDH1A1 (0.54) | KMT2AALDH1A1MEN1CA1CA2 | |
| SCHEMBL17277539 | 0.82 | KIT (0.43) | KMT2AALDH1A1HRH2HRH1MEN1 | |
| SCHEMBL9906394 | 0.77 | KMT2A (0.66) | KMT2AALDH1A1MEN1CYP3A4HPGD | |
| SCHEMBL12169400 | 0.74 | SMN1; SMN2 (0.68) | KMT2AALDH1A1MEN1CYP3A4HPGD | |
| SCHEMBL12169367 | 0.74 | SMN1; SMN2 (0.73) | KMT2AALDH1A1MEN1CYP3A4HPGD | |
| SCHEMBL12075464 | 0.73 | KMT2A (0.65) | KMT2AALDH1A1MEN1UQCRBMAPT | |
| SCHEMBL12169393 | 0.73 | SMN1; SMN2 (0.71) | KMT2AALDH1A1MEN1CYP3A4HPGD | |
| SCHEMBL12062220 | 0.73 | EPHX2 (0.46) | KMT2AALDH1A1HRH2HRH1MEN1 | |
| SCHEMBL12062217 | 0.72 | TSHR (0.41) | KMT2AALDH1A1HRH2HRH1MEN1 | |
| SCHEMBL12061797 | 0.71 | KMT2A (0.58) | KMT2AALDH1A1MEN1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9193731-B2 | Antimicrobial compounds and methods of making and using the same | MELINTA THERAPEUTICS, INC. (US) | 2015-11-24 | — | — | US | disclosed |
| US-20120220566-A1 | Antimicrobial Compounds and Methods of Making and Using the Same | RIB-X PHARMACEUTICALS, INC. (US) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220566-A1 | Antimicrobial Compounds and Methods of Making and Using the Same | MPO, LPO, CAT | KMT2A 4518/4885ALDH1A1 1117/4885CRHBP 3479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.