Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OGA | O60502 | 8/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486699 | 0.81 | ALDH1A1 (0.66) | ALDH1A1LMNARECQLKMT2AGAA | |
| SCHEMBL4590541 | 0.79 | ALDH1A1 (0.64) | ALDH1A1LMNARECQLKMT2AGAA | |
| SCHEMBL3085138 | 0.78 | ALDH1A1 (0.67) | ALDH1A1LMNARECQLKMT2AGAA | |
| SCHEMBL27814718 | 0.78 | ALDH1A1 (0.62) | ALDH1A1LMNARECQLKMT2AGAA | |
| SCHEMBL16854340 | 0.75 | ALDH1A1 (0.72) | ALDH1A1LMNARECQLKMT2AGAA | |
| SCHEMBL18992532 | 0.74 | OGA (0.67) | OGA | |
| SCHEMBL16854335 | 0.72 | ALDH1A1 (0.71) | ALDH1A1LMNARECQLKMT2AGAA | |
| SCHEMBL31633994 | 0.71 | ALDH1A1 (0.47) | ALDH1A1LMNARECQLKMT2AGAA | |
| SCHEMBL31633995 | 0.71 | ALDH1A1 (0.47) | ALDH1A1LMNARECQLKMT2AGAA | |
| SCHEMBL18175699 | 0.71 | ALDH1A1 (0.65) | ALDH1A1LMNARECQLKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841296-B2 | Substituted 1, 4-dioxa-8-azaspiro[4,5]decanes useful as fungicides and a process for the preparation thereof | Council of Scientific and Industrial Research, Anusandhan Bhawan, Rafi Marg (IN) | 2014-09-23 | — | — | US | disclosed |
| US-20120225877-A1 | SUBSTITUTED 1, 4-DIOXA-8-AZASPIRO[4,5]DECANES USEFUL AS FUNGICIDES AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH; ANUSANDHAN BHAWAN, RAFI MARG. (IN) | 2012-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120225877-A1 | SUBSTITUTED 1, 4-DIOXA-8-AZASPIRO[4,5]DECANES USEFUL AS FUNGICIDES AND A PROCESS FOR THE PREPARATION THEREOF | CYP4X1, CYP51A1, CYP1A1 | ALDH1A1 442/4885LMNA 4097/4885RECQL 2222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.