Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16854340 | 0.82 | ALDH1A1 (0.72) | ALDH1A1LMNAKMT2AGAARECQL | |
| SCHEMBL16854335 | 0.75 | ALDH1A1 (0.71) | ALDH1A1LMNAKMT2AGAARECQL | |
| SCHEMBL486699 | 0.75 | ALDH1A1 (0.66) | ALDH1A1LMNAKMT2AGAARECQL | |
| SCHEMBL4590541 | 0.73 | ALDH1A1 (0.64) | ALDH1A1LMNAKMT2AGAARECQL | |
| SCHEMBL3085138 | 0.72 | ALDH1A1 (0.67) | ALDH1A1LMNAKMT2AGAARECQL | |
| SCHEMBL27814718 | 0.72 | ALDH1A1 (0.62) | ALDH1A1LMNAKMT2AGAARECQL | |
| SCHEMBL30664796 | 0.71 | ALDH1A1 (0.57) | ALDH1A1LMNAKMT2AGAARECQL | |
| SCHEMBL12079342 | 0.71 | ALDH1A1 (0.60) | ALDH1A1LMNAKMT2AGAARECQL | |
| SCHEMBL16854472 | 0.68 | CARM1 (0.57) | ALDH1A1LMNAKMT2ARECQLBCHE | |
| SCHEMBL16854349 | 0.67 | ACHE (0.62) | ALDH1A1LMNAKMT2ARECQLBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3085701-A1 | N, N' SUBSTITUTED PIPERIDINAMINE COMPOUNDS, AND PREPARATION METHOD AND USAGE THEREOF | Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China (CN) | 2016-10-26 | — | — | EP | disclosed |