SCHEMBL1208165

SCHEMBL1208165

CC(=O)N1c2ccc(N)cc2Sc2cc(N)ccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOX1 Q9Y5S8 3/20 0.58
▸ MEN1 O00255 2/20 0.51
▸ KMT2A Q03164 2/20 0.51
▸ L3MBTL1 Q9Y468 2/20 0.51
▸ ADRA2A P08913 1/20 0.51
▸ ADRA2B P18089 1/20 0.51
▸ ADRA2C P18825 1/20 0.51
▸ CHRM3 P20309 1/20 0.51
▸ SLC6A2 P23975 1/20 0.51
▸ HTR2C P28335 1/20 0.51
▸ SLC6A4 P31645 1/20 0.51
▸ DRD3 P35462 1/20 0.51
▸ HTR2B P41595 1/20 0.51
▸ SNCA P37840 4/20 0.51
▸ BCHE P06276 7/20 0.41
▸ ACHE P22303 2/20 0.41
▸ MAPK1 P28482 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ CHEK1 O14757 1/20 0.38
▸ AURKA O14965 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29850660 1.00 NOX1 (0.58) NOX1MEN1KMT2AL3MBTL1ADRA2A
Hydrochloric Acid SCHEMBL1929442 0.98 NOX1 (0.56) NOX1MEN1KMT2AL3MBTL1ADRA2A
Ammonia Solution, Strong SCHEMBL1927787 0.98 NOX1 (0.56) NOX1MEN1KMT2AL3MBTL1ADRA2A
SCHEMBL8223437 0.88 NOX1 (0.46) NOX1MEN1KMT2AL3MBTL1ADRA2A
SCHEMBL21752052 0.88 SNCA (0.68) NOX1MEN1KMT2AL3MBTL1ADRA2A
SCHEMBL5452710 0.80 SNCA (0.73) NOX1MEN1KMT2AL3MBTL1SNCA
SCHEMBL29776881 0.80 SNCA (0.73) NOX1MEN1KMT2AL3MBTL1SNCA
SCHEMBL29188165 0.79 NOX1 (0.58) NOX1MEN1KMT2AL3MBTL1SNCA
SCHEMBL17109700 0.79 NOX1 (0.58) NOX1MEN1KMT2AL3MBTL1HTR2C
SCHEMBL14058478 0.78 BCHE (0.64) NOX1MEN1KMT2AL3MBTL1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325557-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. (SG) 2025-10-23 — — US disclosed
US-20250222006-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. (SG) 2025-07-10 — — US disclosed
US-12324810-B2 3, 7-diamino-10H-phenothiazine salts and their use WISTA LABORATORIES LTD. (SG) 2025-06-10 — — US disclosed
US-12215234-B2 Process for the purification of methylene blue RK Pharma Solutions LLC (US) 2025-02-04 — — US disclosed
US-20240245700-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. (SG) 2024-07-25 — — US disclosed
US-20240115580-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. (SG) 2024-04-11 — — US disclosed
US-11951110-B2 3, 7-diamino-10H-phenothiazine salts and their use WISTA LABORATORIES LTD. (SG) 2024-04-09 — — US disclosed
US-11878021-B2 Methods of synthesis and/or purification of diaminophenothiazinium compounds WISTA LABORATORIES LTD. (SG) 2024-01-23 — — US disclosed
CN-109384741-B 3,7-diamino-10H-phenothiazine compound salt and application thereof 维斯塔实验室有限公司 2023-01-06 — — CN disclosed
CN-104606199-B 3, 7-diamino-10H-phenothiazine compound salt and use thereof 维斯塔实验室有限公司 2022-09-13 — — CN disclosed
WO-2009044127-A1 THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES WISTA LABORATORIES LTD. (GB) 2009-04-09 — — WO disclosed
US-20090054419-A1 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. 2009-02-26 — — US disclosed
US-20090054419-A1 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. 2009-02-26 — — US disclosed
US-20090054419-A1 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. 2009-02-26 — — US disclosed
EP-2013191-A2 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE Wista Laboratories Ltd. (SG) 2009-01-14 — — EP disclosed
WO-2008007074-A2 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. (SG) 2008-01-17 — — WO disclosed
WO-2007110627-A2 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. (SG) 2007-10-04 — — WO disclosed
WO-2007110627-A2 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. (SG) 2007-10-04 — — WO disclosed
US-20070129543-A1 PROCESSES FOR PREPARING NOVEL METHYLENE BLUE DERIVATIVE VERFICATION TECHNOLOGIES, INC. (US) 2007-06-07 — — US disclosed
US-7176308-B2 Processes for preparing novel methylene blue derivative VERIFICATION TECHNOLOGIES, INC. (US) 2007-02-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325557-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE PSEN1, PSEN2, APP NOX1 187/4885MEN1 2704/4885KMT2A 2866/4885
US-12324810-B2 3, 7-diamino-10H-phenothiazine salts and their use PSEN1, PSEN2, APP NOX1 347/4885MEN1 3093/4885KMT2A 2987/4885
US-20250222006-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS MB, TPMT, HBB NOX1 1655/4885MEN1 330/4885KMT2A 936/4885
US-20070129543-A1 PROCESSES FOR PREPARING NOVEL METHYLENE BLUE DERIVATIVE MB, HMBS, KIT NOX1 3596/4885MEN1 1294/4885KMT2A 1324/4885
US-11951110-B2 3, 7-diamino-10H-phenothiazine salts and their use PSEN1, PSEN2, APP NOX1 187/4885MEN1 2704/4885KMT2A 2866/4885
US-20240115580-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS MB, TPMT, HBB NOX1 1655/4885MEN1 330/4885KMT2A 936/4885
US-11878021-B2 Methods of synthesis and/or purification of diaminophenothiazinium compounds MB, TPMT, HBB NOX1 1655/4885MEN1 330/4885KMT2A 936/4885
US-20240245700-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE PSEN1, PSEN2, APP NOX1 347/4885MEN1 3093/4885KMT2A 2987/4885
US-20090054419-A1 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE PSEN1, PSEN2, HTT NOX1 490/4885MEN1 327/4885KMT2A 1573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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