Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL1927787

CC(=O)N1c2ccc(N)cc2Sc2cc(N)ccc21.N

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOX1 Q9Y5S8 3/20 0.56
▸ SNCA P37840 4/20 0.50
▸ MEN1 O00255 2/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ L3MBTL1 Q9Y468 2/20 0.50
▸ ADRA2A P08913 1/20 0.50
▸ ADRA2B P18089 1/20 0.50
▸ ADRA2C P18825 1/20 0.50
▸ CHRM3 P20309 1/20 0.50
▸ SLC6A2 P23975 1/20 0.50
▸ HTR2C P28335 1/20 0.50
▸ SLC6A4 P31645 1/20 0.50
▸ DRD3 P35462 1/20 0.50
▸ HTR2B P41595 1/20 0.50
▸ BCHE P06276 7/20 0.40
▸ ACHE P22303 2/20 0.40
▸ MAPK1 P28482 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ CHEK1 O14757 1/20 0.37
▸ AURKA O14965 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29850660 0.98 NOX1 (0.58) NOX1SNCAMEN1KMT2AL3MBTL1
SCHEMBL1208165 0.98 NOX1 (0.58) NOX1SNCAMEN1KMT2AL3MBTL1
Hydrochloric Acid SCHEMBL1929442 0.97 NOX1 (0.56) NOX1SNCAMEN1KMT2AL3MBTL1
SCHEMBL8223437 0.87 NOX1 (0.46) NOX1SNCAMEN1KMT2AL3MBTL1
SCHEMBL21752052 0.87 SNCA (0.68) NOX1SNCAMEN1KMT2AL3MBTL1
SCHEMBL5452710 0.79 SNCA (0.73) NOX1SNCAMEN1KMT2AL3MBTL1
SCHEMBL29776881 0.79 SNCA (0.73) NOX1SNCAMEN1KMT2AL3MBTL1
SCHEMBL29188165 0.77 NOX1 (0.58) NOX1SNCAMEN1KMT2AL3MBTL1
SCHEMBL17109700 0.77 NOX1 (0.58) NOX1SNCAMEN1KMT2AL3MBTL1
SCHEMBL14058478 0.76 BCHE (0.64) NOX1SNCAMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240115580-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. (SG) 2024-04-11 — — US disclosed
US-11878021-B2 Methods of synthesis and/or purification of diaminophenothiazinium compounds WISTA LABORATORIES LTD. (SG) 2024-01-23 — — US disclosed
EP-3121169-B1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LAB LTD (SG) 2022-02-09 — — EP disclosed
US-20210322435-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS Wis Ta Laboratories Ltd. (SG) 2021-10-21 — — US disclosed
US-11045477-B2 Methods of synthesis and/or purification of diaminophenothiazinium compounds WISTA LABORATORIES LTD. (SG) 2021-06-29 — — US disclosed
US-20200261465-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. (SG) 2020-08-20 — — US disclosed
US-20180263999-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. (SG) 2018-09-20 — — US disclosed
US-9980971-B2 Methods of synthesis and/or purification of diaminophenothiazinium compounds WISTA LABORATORIES LTD. (SG) 2018-05-29 — — US disclosed
US-20170273986-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. (SG) 2017-09-28 — — US disclosed
US-9675621-B2 Methods of synthesis and/or purification of diaminophenothiazinium compounds WISTA LABORATORIES LTD. (SG) 2017-06-13 — — US disclosed
US-20130317012-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. (SG) 2013-11-28 — — US disclosed
EP-2057136-B1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LAB LTD (SG) 2013-05-22 — — EP disclosed
US-8440821-B2 Methods of synthesis and/or purification of diaminophenothiazinium compounds WISTA LABORATORIES LTD. (SG) 2013-05-14 — — US disclosed
EP-2457904-A1 Methods of synthesis and/or purification of diaminophenothiazinium compounds Wista Laboratories Ltd. (SG) 2012-05-30 — — EP disclosed
EP-2457905-A1 Methods of synthesis and/or purification of diaminophenothiazinium compounds Wista Laboratories Ltd. (SG) 2012-05-30 — — EP disclosed
US-20110294795-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. 2011-12-01 — — US disclosed
US-7956183-B2 Methods of synthesis and/or purification of diaminophenothiazinium compounds WISTA LABORATORIES LTD. (SG) 2011-06-07 — — US disclosed
US-20090259040-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. (SG) 2009-10-15 — — US disclosed
EP-2057136-A2 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS Wista Laboratories Ltd. (SG) 2009-05-13 — — EP disclosed
WO-2008007074-A2 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. (SG) 2008-01-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180263999-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS MB, TPMT, HBB NOX1 1655/4885SNCA 173/4885MEN1 330/4885
US-20170273986-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS MB, TPMT, HBB NOX1 1655/4885SNCA 173/4885MEN1 330/4885
US-20210322435-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS MB, TPMT, HBB NOX1 1655/4885SNCA 173/4885MEN1 330/4885
US-11045477-B2 Methods of synthesis and/or purification of diaminophenothiazinium compounds MB, TPMT, HBB NOX1 1655/4885SNCA 173/4885MEN1 330/4885
US-20090259040-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS PARK7, SNCA, GRN NOX1 3287/4885SNCA 2/4885MEN1 674/4885
US-20240115580-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS MB, TPMT, HBB NOX1 1655/4885SNCA 173/4885MEN1 330/4885
US-20130317012-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS MAPT, TPMT, UROD NOX1 4259/4885SNCA 227/4885MEN1 50/4885
US-11878021-B2 Methods of synthesis and/or purification of diaminophenothiazinium compounds MB, TPMT, HBB NOX1 1655/4885SNCA 173/4885MEN1 330/4885
US-20110294795-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS MMAB, MB, ABCB7 NOX1 3149/4885SNCA 1425/4885MEN1 20/4885
US-20200261465-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS MB, TPMT, HBB NOX1 1655/4885SNCA 173/4885MEN1 330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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