Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2366519 | 1.00 | MAPT (0.48) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL2366895 | 0.92 | MAPT (0.49) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL12082235 | 0.92 | MAPT (0.49) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL25890179 | 0.81 | KDM4E (0.51) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL18840218 | 0.80 | MAPT (0.49) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL10177918 | 0.80 | MAPT (0.49) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL19433075 | 0.80 | MAPT (0.49) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL13979647 | 0.79 | TDP1 (0.56) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL12082232 | 0.75 | HDAC3 (0.52) | ALDH1A1GAAKMT2AMEN1L3MBTL1 | |
| SCHEMBL2367026 | 0.75 | HDAC3 (0.52) | ALDH1A1GAAKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364293-B1 | NOVEL PYRAZOLE-4-N-ALKOXYCARBOXAMIDES AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-01-23 | — | — | EP | disclosed |
| US-8258169-B2 | Pyrazole-4-N-alkoxycarboxamides as microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2012-09-04 | — | — | US | disclosed |
| US-8258169-B2 | Pyrazole-4-N-alkoxycarboxamides as microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2012-09-04 | — | — | US | disclosed |
| US-20110230537-A1 | NOVEL PYRAZOLE-4-N-ALKOXYCARBOXAMIDES AS MICROBIOCIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-09-22 | — | — | US | disclosed |
| US-20110230537-A1 | NOVEL PYRAZOLE-4-N-ALKOXYCARBOXAMIDES AS MICROBIOCIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-09-22 | — | — | US | disclosed |
| WO-2010063700-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230537-A1 | NOVEL PYRAZOLE-4-N-ALKOXYCARBOXAMIDES AS MICROBIOCIDES | CASP1, CASP14, CD14 | MAPT 4788/4885ALDH1A1 390/4885KDM4E 1247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.