Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 19/20 | 1.00 |
| ▸ | OPRL1 | P41146 | 8/20 | 1.00 |
| ▸ | SCN1A | P35498 | 2/20 | 1.00 |
| ▸ | SCN2A | Q99250 | 2/20 | 1.00 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 1.00 |
| ▸ | DRD4 | P21917 | 7/20 | 0.73 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.73 |
| ▸ | DRD2 | P14416 | 6/20 | 0.73 |
| ▸ | DRD3 | P35462 | 6/20 | 0.73 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.73 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.73 |
| ▸ | HTR2B | P41595 | 5/20 | 0.73 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.73 |
| ▸ | HRH2 | P25021 | 5/20 | 0.73 |
| ▸ | HTR1A | P08908 | 4/20 | 0.73 |
| ▸ | DRD1 | P21728 | 4/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.73 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluperamide SCHEMBL7743934 | 0.99 | OPRM1 (0.98) | OPRM1OPRL1SCN1ASCN2ASCN3A | |
| Fluperamide SCHEMBL29884619 | 0.99 | OPRM1 (0.98) | OPRM1OPRL1SCN1ASCN2ASCN3A | |
| SCHEMBL6893113 | 0.90 | OPRM1 (0.81) | OPRM1OPRL1SCN1ASCN2ASCN3A | |
| Loperamide SCHEMBL28530 | 0.85 | OPRM1 (1.00) | OPRM1OPRL1SCN1ASCN2ASCN3A | |
| Loperamide SCHEMBL12387663 | 0.85 | OPRM1 (1.00) | OPRM1OPRL1SCN1ASCN2ASCN3A | |
| Loperamide SCHEMBL8409779 | 0.85 | OPRM1 (1.00) | OPRM1OPRL1SCN1ASCN2ASCN3A | |
| Loperamide SCHEMBL15048 | 0.84 | OPRM1 (1.00) | OPRM1OPRL1SCN1ASCN2ASCN3A | |
| Loperamide SCHEMBL21327979 | 0.84 | OPRM1 (1.00) | OPRM1OPRL1SCN1ASCN2ASCN3A | |
| Loperamide SCHEMBL8409268 | 0.84 | OPRM1 (1.00) | OPRM1OPRL1SCN1ASCN2ASCN3A | |
| Loperamide SCHEMBL9068543 | 0.84 | OPRM1 (1.00) | OPRM1OPRL1SCN1ASCN2ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107880988-A | Stainless steel environment-friendly molded oil and preparation method thereof | 广州市联诺化工科技有限公司 | 2018-04-06 | — | — | CN | claimed |
| CN-107815344-A | Semi-synthetic cutting fluid of long-life environment-friendly type and preparation method thereof | 广州市联诺化工科技有限公司 | 2018-03-20 | — | — | CN | claimed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| US-8268352-B2 | Modified release composition for highly soluble drugs | TORRENT PHARMACEUTICALS LIMITED (IN) | 2012-09-18 | — | — | US | claimed |
| US-8263125-B2 | Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients | TORRENT PHARMACEUTICALS LIMITED (IN) | 2012-09-11 | — | — | US | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| CN-101330905-A | Freeze-drying process and products obtained thereby | SCIDOSE LLC (US) | 2008-12-24 | — | — | CN | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| EP-0888141-B1 | FILM-FORMING COMPOSITIONS OF ANTIHYPERALGESIC OPIATES AND THEIR USE FOR TREATING HYPERALGESIC CONDITIONS THEREWITH | ADOLOR CORP (US) | 2004-05-26 | — | — | EP | claimed |
| US-6576650-B1 | No central nervous system side effects | REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-06-10 | — | — | US | claimed |
| EP-1119354-A4 | PERIPHERALLY ACTING ANTI-PRURITIC OPIATES | ADOLOR CORP (US) | 2003-02-12 | — | — | EP | claimed |
| JP-2002527392-A | — | — | 2002-08-27 | — | — | JP | claimed |
| EP-1119354-A1 | PERIPHERALLY ACTING ANTI-PRURITIC OPIATES | Adolor Corporation (US) | 2001-08-01 | — | — | EP | claimed |
| WO-2000021530-A1 | PERIPHERALLY ACTING ANTI-PRURITIC OPIATES | ADOLOR CORPORATION (US) | 2000-04-20 | — | — | WO | claimed |
| US-5811078-A | IN A SOLVENT MIXTURE WITH ETHYL OR ISOPROPYL ALCOHOL AND WATER | ADOLOR CORPORATION (US) | 1998-09-22 | — | — | US | claimed |
| US-5798093-A | ADMINISTERING WITH AN ALCOHOL-WATER MIXTURE | ADOLOR CORPORATION (US) | 1998-08-25 | — | — | US | claimed |
| US-5667773-A | Film-forming compositions of antihyperalgesic opiates and method of treating hyperalgesic conditions therewith | ADOLOR CORPORATION (US) | 1997-09-16 | — | — | US | claimed |
| US-4898873-A | α,α-Diaryl-4-aryl-4-hydroxyl-1-piperidinebutanamide, N-oxides and pharmaceutical use | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-02-06 | — | — | US | claimed |