Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12083425 | 0.87 | LMNA (0.38) | LMNACYP2C9 | |
| SCHEMBL28796425 | 0.74 | CRBN (0.36) | LMNACYP2C9 | |
| SCHEMBL12083434 | 0.73 | — | — | |
| SCHEMBL28470467 | 0.70 | — | — | |
| SCHEMBL27610880 | 0.67 | LMNA (0.39) | LMNACYP2C9 | |
| SCHEMBL9451829 | 0.66 | CA1 (0.38) | CA1CA9 | |
| SCHEMBL441725 | 0.66 | — | — | |
| SCHEMBL430902 | 0.64 | CA1 (0.39) | LMNACYP2C9CA1CA9 | |
| SCHEMBL4574758 | 0.64 | — | — | |
| SCHEMBL1262951 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8258345-B2 | Hydroxylation of β-dicarbonyls with zirconium catalysts | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-09-04 | — | — | US | disclosed |
| US-20110196175-A1 | Hydroxylation of Beta-Dicarbonyls with Zirconium Catalysts | FMC CORPORATION | 2011-08-11 | — | — | US | disclosed |
| US-7939685-B2 | Hydroxylation of β-dicarbonyls with zirconium catalysts | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-10 | — | — | US | disclosed |
| US-7939685-B2 | Hydroxylation of β-dicarbonyls with zirconium catalysts | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-10 | — | — | US | disclosed |
| US-20100185014-A1 | Hydroxylation of Beta-Dicarbonyls with Zirconium Catalysts | FMC CORPORATION | 2010-07-22 | — | — | US | disclosed |
| US-20100185014-A1 | Hydroxylation of Beta-Dicarbonyls with Zirconium Catalysts | FMC CORPORATION | 2010-07-22 | — | — | US | disclosed |
| US-7718818-B2 | Hydroxylation of beta-dicarbonyls with zirconium catalysts | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-05-18 | — | — | US | disclosed |
| US-7718818-B2 | Hydroxylation of beta-dicarbonyls with zirconium catalysts | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-05-18 | — | — | US | disclosed |
| US-20080306259-A1 | HYDROXYLATION OF BETA-DICARBONYLS WITH ZIRCONIUM CATALYSTS | FMC CORPORATION | 2008-12-11 | — | — | US | disclosed |
| US-20080306259-A1 | HYDROXYLATION OF BETA-DICARBONYLS WITH ZIRCONIUM CATALYSTS | FMC CORPORATION | 2008-12-11 | — | — | US | disclosed |
| US-7414157-B2 | Hydroxylation of β-dicarbonyls with zirconium catalysts | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100185014-A1 | Hydroxylation of Beta-Dicarbonyls with Zirconium Catalysts | CBR3, CBR1, NOXO1 | LMNA 3105/4885CYP2C9 137/4885CA1 737/4885 |
| US-20110196175-A1 | Hydroxylation of Beta-Dicarbonyls with Zirconium Catalysts | CBR3, CBR1, NOXO1 | LMNA 3105/4885CYP2C9 137/4885CA1 737/4885 |
| US-20080306259-A1 | HYDROXYLATION OF BETA-DICARBONYLS WITH ZIRCONIUM CATALYSTS | CBR3, CBR1, ASPH | LMNA 3881/4885CYP2C9 77/4885CA1 259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.