Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4264199 | 1.00 | TSHR (0.69) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL23787581 | 0.98 | TSHR (0.67) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL12840596 | 0.95 | TSHR (0.63) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL14065638 | 0.94 | TSHR (0.61) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL13023957 | 0.94 | TSHR (0.61) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL13423640 | 0.94 | TSHR (0.61) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL13483552 | 0.94 | TSHR (0.61) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL16728765 | 0.94 | TSHR (0.61) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL12299083 | 0.94 | TSHR (0.61) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL12934641 | 0.94 | TSHR (0.61) | TSHRHPGDMEN1KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865965-B2 | Absorbent article with high and low density portions and skin care agent thereon | KAO CORPORATION (JP) | 2014-10-21 | — | — | US | disclosed |
| US-20120226250-A1 | ABSORBENT ARTICLE | KAO CORPORATION (JP) | 2012-09-06 | — | — | US | disclosed |