SCHEMBL16728765

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12090657	0.94	TSHR (0.69)	TSHRHPGDMEN1KMT2AKDM4E
	SCHEMBL4264199	0.94	TSHR (0.69)	TSHRHPGDMEN1KMT2AKDM4E
	SCHEMBL23787581	0.93	TSHR (0.67)	TSHRHPGDMEN1KMT2AKDM4E
	SCHEMBL12840596	0.90	TSHR (0.63)	TSHRHPGDMEN1KMT2AKDM4E
	SCHEMBL13483552	0.89	TSHR (0.61)	TSHRHPGDMEN1KMT2AKDM4E
	SCHEMBL13023957	0.89	TSHR (0.61)	TSHRHPGDMEN1KMT2AKDM4E
	SCHEMBL14065638	0.89	TSHR (0.61)	TSHRHPGDMEN1KMT2AKDM4E
	SCHEMBL12934641	0.89	TSHR (0.61)	TSHRHPGDMEN1KMT2ACNR1
	SCHEMBL12299083	0.89	TSHR (0.61)	TSHRHPGDMEN1KMT2AKDM4E
	SCHEMBL13423640	0.89	TSHR (0.61)	TSHRHPGDMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.