SCHEMBL13423640 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	TSHR	P16473	1/20	0.61

▸	HPGD	P15428	4/20	0.47

▸	MEN1	O00255	1/20	0.47

▸	KMT2A	Q03164	1/20	0.47

▸	KDM4E	B2RXH2	2/20	0.45

▸	LMNA	P02545	1/20	0.45

▸	ALDH1A1	P00352	5/20	0.43

▸	HTT	P42858	1/20	0.42

▸	SMN1; SMN2	Q16637	1/20	0.42

▸	MAPT	P10636	2/20	0.40

▸	CYP2C19	P33261	1/20	0.39

▸	FAAH	O00519	1/20	0.39

▸	RECQL	P46063	1/20	0.38

▸	CNR1	P21554	2/20	0.38

▸	CNR2	P34972	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4264199	0.94	TSHR (0.69)	TSHRHPGDMEN1KMT2AKDM4E
SCHEMBL12090657	0.94	TSHR (0.69)	TSHRHPGDMEN1KMT2AKDM4E
SCHEMBL23787581	0.93	TSHR (0.67)	TSHRHPGDMEN1KMT2AKDM4E
SCHEMBL12840596	0.90	TSHR (0.63)	TSHRHPGDMEN1KMT2AKDM4E
SCHEMBL13431136	0.89	TSHR (0.76)	TSHRHPGDMEN1KMT2AKDM4E
SCHEMBL16728765	0.89	TSHR (0.61)	TSHRHPGDMEN1KMT2AKDM4E
SCHEMBL13023957	0.89	TSHR (0.61)	TSHRHPGDMEN1KMT2AKDM4E
SCHEMBL13483552	0.89	TSHR (0.61)	TSHRHPGDMEN1KMT2AKDM4E
SCHEMBL14065638	0.89	TSHR (0.61)	TSHRHPGDMEN1KMT2AKDM4E
SCHEMBL12299083	0.89	TSHR (0.61)	TSHRHPGDMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2010046076-A1	COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR	KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE)	2010-04-29	—	—	WO	disclosed