SCHEMBL12090909

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4136357	0.82	OPRM1 (0.39)	CNR2MAPT
	SCHEMBL10314064	0.81	CNR2 (0.34)	CCNB2CCNE2CDK1FGFR1CDK4
	SCHEMBL12090602	0.78	POLB (0.40)	CNR2
	SCHEMBL12090604	0.78	CDK4 (0.33)	CCNB2CCNE2CDK1FGFR1CDK4
	SCHEMBL12091014	0.77	JAK2 (0.31)	CCNB2CCNE2CDK1FGFR1CDK4
	SCHEMBL9850735	0.70	CNR2 (0.50)	CCNB2CCNE2CDK1FGFR1CDK4
	SCHEMBL1376936	0.69	CDK4 (0.54)	CDK4CCND1CCND2CCND3MAPT
	SCHEMBL11562270	0.69	KDM4E (0.49)	CDK4CCND1CCND2CCND3PDE4A
	SCHEMBL14361558	0.69	CNR1 (0.31)	CNR2CNR1
	SCHEMBL4136327	0.67	ALDH1A1 (0.41)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.