Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.43 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507245 | 0.86 | AOC3 (0.63) | AOC3KCNH2CYP2A6TSHRAPP | |
| SCHEMBL12092462 | 0.85 | KDM4E (0.50) | AOC3KCNH2APPALDH1A1KDM4E | |
| SCHEMBL12091866 | 0.81 | KMO (0.56) | AOC3KCNH2MAPTTSHRAPP | |
| SCHEMBL12091794 | 0.81 | AOC3 (0.52) | AOC3KCNH2TSHRAPPCYP1A2 | |
| SCHEMBL12092461 | 0.76 | TGFBR1 (0.44) | NPSR1POLBALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL16016104 | 0.76 | APP (0.51) | AOC3KCNH2MAPTTSHRAPP | |
| SCHEMBL7808056 | 0.75 | KMT2A (0.67) | AOC3KCNH2CYP2A6MAPTAPP | |
| SCHEMBL13425013 | 0.74 | KMT2A (0.55) | TSHRAPPALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL15694852 | 0.74 | AOC3 (0.57) | AOC3KCNH2CYP2A6MAPTNPSR1 | |
| SCHEMBL12091860 | 0.73 | KMO (0.54) | AOC3KCNH2TSHRAPPABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120225873-A1 | COMPOUNDS FOR ALZHEIMER'S DISEASE | MYREXIS, INC. (US) | 2012-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120225873-A1 | COMPOUNDS FOR ALZHEIMER'S DISEASE | PSEN2, CHAT, PSEN1 | AOC3 38/4885KCNH2 1726/4885CYP2A6 1111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.