Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 5/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12091794 | 0.91 | AOC3 (0.52) | AOC3KCNH2CYP1A2POLBCYP3A4 | |
| SCHEMBL12092463 | 0.86 | AOC3 (0.52) | AOC3KCNH2CYP1A2POLBCYP3A4 | |
| SCHEMBL12091866 | 0.86 | KMO (0.56) | AOC3KCNH2CYP1A2POLBCYP3A4 | |
| SCHEMBL1878805 | 0.84 | HAO1 (0.58) | AOC3KCNH2CYP2C9APPHAO1 | |
| SCHEMBL12091796 | 0.83 | APP (0.53) | AOC3KCNH2APPHAO1ALDH1A1 | |
| SCHEMBL22171609 | 0.80 | ALDH1A1 (0.53) | AOC3KCNH2APPHAO1ALDH1A1 | |
| SCHEMBL13425022 | 0.80 | HAO1 (0.62) | AOC3KCNH2CYP2C9APPHAO1 | |
| SCHEMBL19219061 | 0.80 | AOC3 (0.54) | AOC3KCNH2APPHAO1ALDH1A1 | |
| SCHEMBL29429079 | 0.80 | CYP11B1 (0.46) | AOC3KCNH2CYP1A2POLBCYP3A4 | |
| SCHEMBL28693222 | 0.80 | CYP11B1 (0.46) | AOC3KCNH2CYP1A2POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296873-B1 | DIRECT POSITIVE DIMETHINE CYANINE DYES CONTAINING 1-ARYL-2-HETEROARYL INDOLE NUCLEUS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-08 | — | — | EP | claimed |
| EP-0296873-A2 | Direct positive dimethine cyanine dyes containing 1-aryl-2-heteroaryl indole nucleus | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-12-28 | — | — | EP | claimed |
| EP-0296873-B1 | DIRECT POSITIVE DIMETHINE CYANINE DYES CONTAINING 1-ARYL-2-HETEROARYL INDOLE NUCLEUS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-08 | — | — | EP | disclosed |
| US-5004812-A | Phenyl-pyridyl-indole Intermediates For Desensitizing Dyes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-02 | — | — | US | disclosed |
| US-4927933-A | PHOTOGRAPHIC FILMS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-05-22 | — | — | US | disclosed |
| US-4839271-A | SENSITIZERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-06-13 | — | — | US | disclosed |
| EP-0296873-A2 | Direct positive dimethine cyanine dyes containing 1-aryl-2-heteroaryl indole nucleus | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-12-28 | — | — | EP | disclosed |