Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | TSHR | P16473 | 3/20 | 0.72 |
| ▸ | ESR1 | P03372 | 3/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.72 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.72 |
| ▸ | KDR | P35968 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | STS | P08842 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.58 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29311434 | 0.98 | ALDH1A1 (0.70) | ALDH1A1TSHRESR1TDP1CHRM1 | |
| SCHEMBL49950 | 0.92 | ALDH1A1 (0.84) | ALDH1A1TSHRESR1TDP1CHRM1 | |
| SCHEMBL27647510 | 0.90 | ALDH1A1 (0.81) | ALDH1A1TSHRESR1TDP1CHRM1 | |
| SCHEMBL27667922 | 0.90 | ALDH1A1 (0.81) | ALDH1A1TSHRESR1TDP1CHRM1 | |
| SCHEMBL27647504 | 0.90 | ALDH1A1 (0.81) | ALDH1A1TSHRESR1TDP1CHRM1 | |
| SCHEMBL27647586 | 0.90 | ALDH1A1 (0.81) | ALDH1A1TSHRESR1TDP1CHRM1 | |
| Methane SCHEMBL27699232 | 0.90 | ALDH1A1 (0.81) | ALDH1A1TSHRESR1TDP1CHRM1 | |
| SCHEMBL27647501 | 0.90 | ALDH1A1 (0.81) | ALDH1A1TSHRESR1TDP1CHRM1 | |
| SCHEMBL28758641 | 0.90 | ALDH1A1 (0.81) | ALDH1A1TSHRESR1TDP1CHRM1 | |
| SCHEMBL27667930 | 0.90 | ALDH1A1 (0.81) | ALDH1A1TSHRESR1TDP1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914816-B2 | Methods and materials for depolymerizing polyesters | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2018-03-13 | — | — | US | disclosed |
| CN-105492688-B | Treatment agent for synthetic fibers and use thereof | 松本油脂制药株式会社 | 2017-05-24 | — | — | CN | disclosed |
| US-20170081482-A1 | GRAPHENE REINFORCED POLYETHYLENE TEREPHTHALATE | WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT | 2017-03-23 | — | — | US | disclosed |
| CN-105492688-A | Treatment agent for synthetic fibers and use thereof | MATSUMOTO YUSHI-SEIYAKU CO LTD | 2016-04-13 | — | — | CN | disclosed |
| US-20160060419-A1 | METHODS AND MATERIALS FOR DEPOLYMERIZING POLYESTERS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2016-03-03 | — | — | US | disclosed |
| US-9255194-B2 | Methods and materials for depolymerizing polyesters | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2016-02-09 | — | — | US | disclosed |
| US-20150105532-A1 | METHODS AND MATERIALS FOR DEPOLYMERIZING POLYESTERS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-04-16 | — | — | US | disclosed |
| CN-104364372-A | Recombinant microorganism | CARBIOS | 2015-02-18 | — | — | CN | disclosed |
| CN-104039197-A | Cosmetic Applicator | KAO CORP | 2014-09-10 | — | — | CN | disclosed |
| US-20130251778-A1 | MEDICAL DEVICES FOR THERAPEUTIC AGENT DELIVERY WITH POLYMERIC REGIONS THAT CONTAIN COPOLYMERS HAVING BOTH SOFT SEGMENTS AND UNIFORM LENGTH HARD SEGMENTS | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2013-09-26 | — | — | US | disclosed |
| US-8541477-B2 | Methods of depolymerizing terephthalate polyesters | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-09-24 | — | — | US | disclosed |
| US-8440214-B2 | Medical devices for therapeutic agent delivery with polymeric regions that contain copolymers having both soft segments and uniform length hard segments | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2013-05-14 | — | — | US | disclosed |
| US-20120223270-A1 | METHODS OF DEPOLYMERIZING TEREPHTHALATE POLYESTERS | KING ABDULAZIZ CITY FOR SCIENCE AND TECHNOLOGY (SA) | 2012-09-06 | — | — | US | disclosed |
| US-20110207168-A1 | Fiber-Based Biosensors for Use in Detecting the Presence of a Biologically Active Substance | NATIONAL SCIENCE FOUNDATION | 2011-08-25 | — | — | US | disclosed |
| US-7615580-B2 | Ester alcohols and substituted carbamates thereof for minimizing deterioration of polyurethane foams | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2009-11-10 | — | — | US | disclosed |
| US-7544800-B2 | Catalytic depolymerization of polymers containing electrophilic linkages using nucleophilic reagents | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2009-06-09 | — | — | US | disclosed |
| US-20080213823-A1 | CAPILLARY-CHANNELED POLYMER FILM FLOW CYTOMETRY | CLEMSON UNIVERSITY | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120223270-A1 | METHODS OF DEPOLYMERIZING TEREPHTHALATE POLYESTERS | DDT, TRHDE, TERT | ALDH1A1 2617/4885TSHR 1355/4885ESR1 3395/4885 |
| US-20150105532-A1 | METHODS AND MATERIALS FOR DEPOLYMERIZING POLYESTERS | TKT, DERA, KHK | ALDH1A1 978/4885TSHR 4044/4885ESR1 3294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.