Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.43 |
| ▸ | MMP13 | P45452 | 5/20 | 0.43 |
| ▸ | MMP9 | P14780 | 4/20 | 0.43 |
| ▸ | MMP3 | P08254 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | MMP14 | P50281 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464751 | 0.85 | MMP2 (0.57) | MMP2MMP13MMP9MMP3MMP8 | |
| SCHEMBL12095844 | 0.81 | CNR2 (0.56) | MMP2MMP13MMP9MMP3MMP8 | |
| SCHEMBL12095680 | 0.81 | GCK (0.46) | MMP2MMP13MMP9MMP3MMP8 | |
| SCHEMBL1464586 | 0.80 | MAPT (0.48) | MMP2MMP13MMP9MMP3MMP8 | |
| SCHEMBL12095604 | 0.78 | MMP2 (0.48) | MMP2MMP13MMP9MMP3MMP8 | |
| SCHEMBL12095632 | 0.77 | MMP9 (0.42) | MMP2MMP13MMP9MMP3MMP8 | |
| SCHEMBL12095657 | 0.76 | MMP2 (0.46) | MMP2MMP13MMP9MMP3MMP8 | |
| SCHEMBL12095949 | 0.73 | CNR2 (0.47) | CNR2MAPK14MAPK13MAPTMAPK12 | |
| SCHEMBL12827697 | 0.72 | MMP2 (0.55) | MMP2MMP13MMP9MMP3MMP8 | |
| SCHEMBL1464830 | 0.69 | CNR2 (0.47) | CNR2MAPK14MAPK13RAF1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-B1 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2012-09-12 | — | — | EP | claimed |